Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. [PDF]
, 2017 Phospholipid-based deformable nanovesicles (DNVs) that have flexibility in shape offer an adaptable and facile method to encapsulate diverse classes of therapeutics and facilitate localized transdermal delivery while minimizing systemic exposure. Here we
Alam, Mohammad Parvez +7 more
core +2 more sources
Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]
, 2016 Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana +3 more
core +2 more sources
A 3D-printed microfluidic-enabled hollow microneedle architecture for transdermal drug delivery. [PDF]
, 2019 Embedding microfluidic architectures with microneedles enables fluid management capabilities that present new degrees of freedom for transdermal drug delivery.
Akhtar, Farooq +11 more
core +2 more sources
Rationalising polymer selection for supersaturated film forming systems produced by an aerosol spray for the transdermal delivery of methylphenidate [PDF]
, 2017 Film forming systems offer a number of advantages for topical and transdermal drug delivery, in particular enabling production of a supersaturated state which can greatly improve drug absorption and bioavailability.
Brown, Marc B. +4 more
core +3 more sources
Pharmaceutics, 2022 Microneedles (MNs) as a novel transdermal drug delivery system have shown great potential for therapeutic and disease diagnosis applications by continually providing minimally invasive, portable, cost-effective, high bioavailability, and easy-to-use ...
Qinying Yan +6 more
doaj +1 more source
Transdermal evaluation of caffeine in different formulations and excipients [PDF]
, 2013 Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente +7 more
core +2 more sources
Novel chemical permeation enhancers for transdermal drug delivery
Asian Journal of Pharmaceutical Sciences, 2014 Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Yang Chen +4 more
doaj +1 more source
Sonophoresis Using Ultrasound Contrast Agents: Dependence on Concentration. [PDF]
PLoS ONE, 2016 Sonophoresis can increase skin permeability to various drugs in transdermal drug delivery. Cavitation is recognized as the predominant mechanism of sonophoresis.
Donghee Park +10 more
doaj +1 more source
Drug Delivery, 2023 Methotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is greatly limited by the adverse effects and poor patient compliance caused by traditional oral administration or injection.
Weiman Zhao +5 more
doaj +1 more source
Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]
, 2012 Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed +3 more
core +2 more sources