Results 1 to 10 of about 20,575,683 (284)

Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo

International Journal of Nanomedicine, 2011
Ji-Hui Zhao, Li Ji, Hui Wang, Zhi-Qiang Chen, Yong-Tai Zhang, Ying Liu, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaObjective: To deliver 2,3,5,6-tetramethylpyrazine ...
Zhao JH, Ji L, Wang H, Chen ZQ, Zhang YT, Liu Y, Feng NP   +6 more
doaj   +1 more source

An insight into pharmaceutical challenges with ionic liquids: where do we stand in transdermal delivery?

Frontiers in Bioengineering and Biotechnology
Ionic liquids (ILs) represent an exciting and promising solution for advancing drug delivery platforms. Their unique properties, including broad chemical diversity, adaptable structures, and exceptional thermal stability, make them ideal candidates for ...
Ankit Jain, Ashok K. Shakya, Shiv Kumar Prajapati, Mamdouh Eldesoqui, Nishi Mody, Sanjay K. Jain, Rajashri R. Naik, Umesh K. Patil   +7 more
doaj   +1 more source

Improving the stability and transdermal permeability of phycocyanin loaded cubosomes

Frontiers in Nanotechnology
Instability and low transdermal permeability of protein antioxidants are major obstacles to resist oxidative stress in transdermal drug delivery system.
Chune Zhu, Wenjuan Duan, Hui Jing, Jieyu Long, Ying Huang, Di Huang, Chuanbin Wu, Chuanbin Wu   +7 more
doaj   +1 more source

Wearable ultrasound microneedle patch for on-demand and sustained management of gouty arthritis

npj Flexible Electronics
Conventional microneedle-based transdermal delivery is often limited by passive diffusion or endogenous stimuli, offering poor control over release kinetics and insufficient penetration into deep tissues.
Shuxin Zhang, Zhengming Zhou, Litong Chen, Yu-Jia Zeng, Tailin Xu   +4 more
doaj   +1 more source

Advance and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System. [PDF]

Pharmaceutics, 2023
Cheng T, Tai Z, Shen M, Li Y, Yu J, Wang J, Zhu Q, Chen Z.   +7 more
europepmc   +1 more source

Microneedles: an emerging transdermal drug delivery system

Journal of Pharmacy and Pharmacology, 2012
Abstract Objectives One of the thrust areas in drug delivery research is transdermal drug delivery systems (TDDS) due to their characteristic advantages over oral and parenteral drug delivery systems.
Shital H, Bariya, Mukesh C, Gohel, Tejal A, Mehta, Om Prakash, Sharma   +3 more
openaire   +2 more sources

Continuous Drug Release by Sea Anemone Nematostella vectensis Stinging Microcapsules

Marine Drugs, 2014
Transdermal delivery is an attractive option for drug delivery. Nevertheless, the skin is a tough barrier and only a limited number of drugs can be delivered through it. The most difficult to deliver are hydrophilic drugs.
Yossi Tal, Ari Ayalon, Agnesa Sharaev, Zoya Kazir, Vera Brekhman, Tamar Lotan   +5 more
doaj   +1 more source

Microorganism microneedle micro-engine depth drug delivery

Nature Communications
As a transdermal drug delivery method, microneedles offer minimal invasiveness, painlessness, and precise in-situ treatment. However, current microneedles rely on passive diffusion, leading to uncontrollable drug penetration.
Bin Zheng, Qiuya Li, Laiping Fang, Xiaolu Cai, Yan Liu, Yanhong Duo, Bowen Li, Zhengyu Wu, Boxi Shen, Yang Bai, Shi-Xiang Cheng, Xingcai Zhang   +11 more
doaj   +1 more source

Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing

Frontiers in Pharmacology
Topical drug delivery is widely used in various diseases because of the advantages of not passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first-pass effect, and reaching the lesion directly to reduce ...
Lin Zhao, Lin Zhao, Jiamei Chen, Jiamei Chen, Bai Bai, Bai Bai, Guili Song, Guili Song, Jingwen Zhang, Jingwen Zhang, Han Yu, Han Yu, Shiwei Huang, Shiwei Huang, Zhang Wang, Zhang Wang, Guanghua Lu, Guanghua Lu, Guanghua Lu   +18 more
doaj   +1 more source

Drug Delivery to the Eye with a Transdermal Therapeutic System.

Biological and Pharmaceutical Bulletin, 2003
A matrix-type transdermal therapeutic system was developed for treating diseases of the eye where it is difficult for drug molecules to reach with conventional topical instillation. Prednisolone was employed as a model drug. An in vivo study using rats showed that the daily application of the patch maintained a constant plasma concentration of the drug,
Isowaki, Akiharu, Ohtori, Akira, Matsuo, Yumi, Tojo, Kakuji   +3 more
openaire   +3 more sources