Results 101 to 110 of about 329,610 (317)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Transducers with Origin Information [PDF]
, 2014 Call a string-to-string transducer regular if it can be realised by one of the following equivalent models: mso transductions, two-way deterministic automata with output, and streaming transducers with registers. This paper proposes to treat origin information as part of the semantics of a regular string-to-string transducer.
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2016 This thesis contains transducer systems. It describes properties of various translation models. It demonstrates translation power of these models on concrete examples. This thesis focuses mostly on finite and pushdown transducers.
Hnat, Peter
core +4 more sources
Electrochemical vibration sensor for low frequency detection: model, design and manufacture
Microsystems & NanoengineeringVibration sensors play a crucial role in resource exploration, structural health monitoring, and seismic activity detection. Conventional vibration sensors, primarily including electromagnetic, capacitive, piezoelectric, and fiber optic types, have been ...
Wenlang Zhao +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A multi-region flexible neural interface for behavioral state decoding in freely moving mice
Microsystems & NanoengineeringHigh-density, long-term stable decoding of whole-brain function is crucial for advancing basic neuroscience research and developing neural disorder therapies.
Ye Tian +14 more
doaj +1 more source
Sensors, 2010 Microorganisms show attractant and repellent responses to survive in the various environments in which they live. Those phototaxic (to light) and chemotaxic (to chemicals) responses are regulated by membrane-embedded receptors and transducers.
Daisuke Suzuki +4 more
doaj +1 more source
Application and development of finite element techniques for transducer design and analysis [PDF]
, 1999 Ocean acoustic tomography (OAT) is a method for mapping the physical characteristics of the world’s oceans. This technique enables the properties of a region of ocean – its temperatures, salinities, densities, and current speeds – to be inferred by ...
Bayliss, Clive
core