Results 61 to 70 of about 294,368 (303)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Tactile sensing means for prosthetic limbs [PDF]

, 1973
An improved prosthetic device characterized by a frame and a socket for mounting on the stump of a truncated human appendage is described. Flexible digits extend from the distal end and transducers located within the digits act as sensing devices for ...
Scott, W. L.
core   +1 more source

The mathematical theory of resonant transducers in a spherical gravity wave antenna [PDF]

, 2000
The rigoruos mathematical theory of the coupling and response of a spherical gravitational wave detector endowed with a set of resonant transducers is presented and developed.
Astone P., Dhurandhar S. V., Dhurandhar S. V., Dhurandhar S. V., Forward F., Hamilton W. O., Har'el Z., J. A. Lobo, Lobo J. A., Magalhaes N. S., Magalhaes N. S., Merkowitz S. M., Merkowitz S. M.   +12 more
core   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Electrical-Spin Transduction for CMOS-Spintronic Interface and Long-Range Interconnects

IEEE Journal on Exploratory Solid-State Computational Devices and Circuits, 2017
We propose circuits for efficient transduction between electrical and spin signals and compare designs for long-range spintronic interconnects based on transducers and repeaters.
Rouhollah Mousavi Iraei, Sasikanth Manipatruni, Dmitri E. Nikonov, Ian A. Young, Azad Naeemi   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Load distribution during sit-stand-sit using an instrumented chair [PDF]

, 2005
Paper examining the forces through the body during standing up and sitting down by means of force plates and ...
Nicol, A.C., Wilson, Susan Katherine Mcgregor   +1 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Coupled acoustoplasmonic resonators: the role of geometrical symmetries

Nanophotonics
Acoustoplasmonic resonators, such as nanobars and crosses, are efficient acousto-optical transducers. The excitation of mechanical modes in these structures strongly depends on the spatial profile of the eigenmodes of the resonator. Using a system of two
Castillo López de Larrinzar Beatriz, García Jorge M., Xiang Chushuang, Lanzillotti-Kimura Norberto D., García-Martín Antonio   +4 more
doaj   +1 more source

Remote Radar Based on Chaos Generation and Radio Over Fiber

IEEE Photonics Journal, 2014
An ultrawideband (UWB) radar system for remote ranging based on microwave-photonic chaotic signal generation and fiber-optic distribution is proposed and demonstrated experimentally.
Mingjiang Zhang, Yongning Ji, Yongning Zhang, Yuan Wu, Hang Xu, Weipeng Xu   +5 more
doaj   +1 more source