Results 61 to 70 of about 346,421 (355)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Titanium Nitride Nanoparticles as Plasmonic Solar Heat Transducers

, 2016
We demonstrate that lossy plasmonic resonances of nanoparticles are broad enough to cover the majority of the solar spectrum and highly efficient for absorbing sunlight.
S. Ishii, R. P. Sugavaneshwar, T. Nagao
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Electrical-Spin Transduction for CMOS-Spintronic Interface and Long-Range Interconnects

IEEE Journal on Exploratory Solid-State Computational Devices and Circuits, 2017
We propose circuits for efficient transduction between electrical and spin signals and compare designs for long-range spintronic interconnects based on transducers and repeaters.
Rouhollah Mousavi Iraei, Sasikanth Manipatruni, Dmitri E. Nikonov, Ian A. Young, Azad Naeemi   +4 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Ultrahigh Frequency (100 MHz–300 MHz) Ultrasonic Transducers for Optical Resolution Medical Imagining

Scientific Reports, 2016
High resolution ultrasonic imaging requires high frequency wide band ultrasonic transducers, which produce short pulses and highly focused beam. However, currently the frequency of ultrasonic transducers is limited to below 100 MHz, mainly because of the
Chunlong Fei, Chunlong Fei, C. Chiu, Xiaoyang Chen, Zeyu Chen, Jianguo Ma, B. Zhu, K. Shung, Qifa Zhou, Qifa Zhou   +9 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Coupled acoustoplasmonic resonators: the role of geometrical symmetries

Nanophotonics
Acoustoplasmonic resonators, such as nanobars and crosses, are efficient acousto-optical transducers. The excitation of mechanical modes in these structures strongly depends on the spatial profile of the eigenmodes of the resonator. Using a system of two
Castillo López de Larrinzar Beatriz, García Jorge M., Xiang Chushuang, Lanzillotti-Kimura Norberto D., García-Martín Antonio   +4 more
doaj   +1 more source

Combined Attenuation and High-Resolution Fault Measurements Using Chaos-OTDR

IEEE Photonics Journal, 2015
We propose a combined attenuation and high-resolution fault measurement method using chaos optical time-domain reflectometry (OTDR). Utilizing the pulse-modulated chaotic light and correlation operation, this technique realizes fiber attenuation ...
Xiangyu Dong, Anbang Wang, Jianguo Zhang, Hong Han, Tong Zhao, Xianglian Liu, Yuncai Wang   +6 more
doaj   +1 more source

Advances in Random Fiber Lasers and Their Sensing Application

Sensors, 2020
Compared with conventional laser, random laser (RL) has no resonant cavity, reducing the requirement of cavity design. In recent years, the random fiber laser (RFL), a novel kind of RL, has made great progress in theories and experiments.
Hong Chen, Shaohua Gao, Mingjiang Zhang, Jianzhong Zhang, Lijun Qiao, Tao Wang, Fei Gao, Xinxin Hu, Shichuan Li, Yicheng Zhu   +9 more
doaj   +1 more source