Results 201 to 210 of about 2,619,685 (255)

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

A panoramic analysis of keloid pathogenesis: multidimensional network regulation of genetics-immunity-metabolism-mechanical force. [PDF]

Front Immunol
Liu M.
europepmc   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

StitchR-based dual-AAV delivery strategies enable efficient transduction of defined neural cell populations. [PDF]

Mol Brain
Luo N, Gao Y, Han Z, Su P, Xu F, Lin K.
europepmc   +1 more source

Blending With Insulating Polymers Enables Stable Anti‐Ambipolar Characteristics in n‐Type Organic Mixed‐Conductors for Heterogeneous Spiking Neurons

Advanced Materials, EarlyView.
A polymer blend of n‐type OMIEC P(gNDI‐gT2) with insulating PMMA yields mechanically stabilized, anti‐ambipolar organic electrochemical transistors (OECTs) with tunable ionic‐electronic transport. This blending allows low‐power, fast‐spiking heterogeneous Hodgkin–Huxley neurons, enabling biomimetic frequency deconvolution and reservoir computing, which
Zachary Laswick, Ariel Lifer, Catherine Beaumont, Liad Hayoun, Priscila Cavassin, Zeinab Hamid, Dilara Meli, William Dupont, Lincoln J. Lauhon, Iain McCulloch, Gitti L. Frey, Giovanni Maria Matrone, Jonathan Rivnay   +12 more
wiley   +1 more source

Gene Therapy for Corneal Diseases. [PDF]

BioTech (Basel)
Bhujel B, Eah KS, Kang SS, Chung HS, Kim JY.   +4 more
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Viral Platforms and Synthetic Nanoparticles in Transforming CAR-T Cell Therapy: A Review of Recent Experimental Advances in Enhancing Safety and Efficacy. [PDF]

Med Sci Monit
Wójcik K, Jankowska K, Olszewski J, Gałuszewski M, Bielecka-Wajdman A.   +4 more
europepmc   +1 more source