Results 231 to 240 of about 409,721 (264)
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A combined genetic and biochemical approach to mammalian signal transduction
Australian and New Zealand Journal of Medicine, 1995Abstract:The last five years have seen a rapid increase in interest and understanding of signal transduction pathways. While the description of such pathways has become more detailed and complex, a number of consistent findings have emerged. Modular domains, such as SH2 and SH3 domains, are present on a wide variety of proteins and mediate specific ...
N G, Della +4 more
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Genetic dissection of R gene signal transduction pathways
Current Opinion in Plant Biology, 1998Mutant screens have identified several genes in tomato, barley and Arabidopsis that are required for the function of specific plant disease resistance (R) genes. Two of these genes, NDR1 and EDS1, have recently been cloned from Arabidopsis. Most Arabidopsis R genes require NDR1 or EDS1, but not both.
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APC, Signal transduction and genetic instability in colorectal cancer
Nature Reviews Cancer, 2001Colorectal cancer arises through a gradual series of histological changes, each of which is accompanied by a specific genetic alteration. In general, an intestinal cell needs to comply with two essential requirements to develop into a cancer: it must acquire selective advantage to allow for the initial clonal expansion, and genetic instability to allow
R, Fodde, R, Smits, H, Clevers
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Genetic analysis of the sevenless signal transduction pathway of Drosophila
Development, 1993ABSTRACT The specification of tlie R7 photoreceptor cell fate in the devloping eye of Drosophila depends on the local activation of the sevenless (sev) receptor tyrosine kinase (RTK) by boss, a protein expressed on the membrane of the neighboring RS cell.
Hafen, E. +5 more
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Molecular and genetic analysis of signal transduction in higher plants
Current Biology, 1992Plant scientists have long recognized the complexity of responses to environmental and hormonal signals that provide the basis for plant growth and development. The systematic isolation and analysis of mutations that disrupt signal transduction and prevent the appropriate physiological response provides an important resource for studying these ...
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Genetic analysis of ABA signal transduction pathways
Trends in Plant Science, 1998Abstract The plant hormone abscisic acid (ABA) has been demonstrated to modulate a variety of physiological processes, including seed dormancy, leaf water relations and adaptation to environmental stresses such as cold, drought and salinity. Recent analysis of Arabidopsis mutants with altered responses to ABA is now beginning to indicate the ...
Dario Bonetta, Peter McCourt
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Transduction of linked genetic characters of the host by bacteriophage P1
Virology, 1955The temperate bacteriophage P1 acts as transducing agent for a large variety of genetic characteristics of strains of Escherichia coli and of Shigella dysenteriae. In E. coli strain K12, markers that behave as closely linked in sexual crosses can be transduced jointly. The frequency of joint transduction decreases sharply with decreasing linkage.
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Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Mary-Ellen Taplin +2 more
exaly
Genetic transduction in Bacillussubtilis
Biochemical and Biophysical Research Communications, 1961openaire +2 more sources
Family Physicians and Referrals of Low-risk Women for BRCA1/2 Genetic Services
Ca-A Cancer Journal for Clinicians, 2009M D Pinkowish
exaly