Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review
Advanced Healthcare Materials, EarlyView.This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli +2 more
wiley +1 more source
A <i>Campylobacter jejuni</i> sensor phosphatase-driven two-component system integrates metabolic phosphodonors as cues in signal transduction. [PDF]
Proc Natl Acad Sci U S ARuiz N, Hendrixson DR.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis +19 more
wiley +1 more source
Multi-omics analysis reveals insights into the key genes involved in polysaccharide biosynthesis induced by red light intensity in Platostoma palustre. [PDF]
BMC Plant BiolWei F, Quan C, Xu M, Tang D.
europepmc +1 more source
Genetic Dissection of Plastid-Nuclear Signal Transduction
Nippon Nōgeikagaku Kaishi, 1997 openaire +2 more sources
Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue
Advanced Healthcare Materials, EarlyView.Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri +6 more
wiley +1 more source
Emerging Technologies Tackling Adeno-Associated Viruses (AAV) Immunogenicity in Gene Therapy Applications. [PDF]
PharmaceuticsEgorova T, Starikova A, Polikarpova A.
europepmc +1 more source
Related searches:
Genetics of signal transduction in invertebrates
Current Opinion in Genetics & Development, 1994Receptor tyrosine kinases regulate a number of different cell fate decisions during invertebrate development. Genetic analysis of the signal transduction pathways activated by these kinases suggests that they converge upon a common pathway involving Ras and a cascade of cytoplasmic kinases, diverging again in the nucleus with the regulation of specific
B, Dickson, E, Hafen
openaire +2 more sources
Genetic approaches to mechanosensory transduction
Current Opinion in Neurobiology, 1995Genetic approaches in several organisms provide the means of solving a previously intractable problem: characterizing the molecular foundations of the mechanical senses. In nematode mechanosensory cells, members of a novel class of epithelial ion channel subunits have been implicated as components of a mechanically gated channel.
M, Kernan, C, Zuker
openaire +2 more sources
Chemical genetic analysis of signal transduction pathways
Expert Opinion on Therapeutic Targets, 2006Covalent modification of proteins by phosphorylation represents a major mechanism of signal transduction that contributes to many physiological and pathophysiological processes. The enzymes that regulate protein phosphorylation (e.g., protein kinases and phosphatases) are, therefore, potential targets for the rational design of small-molecule drugs for
Anja, Jaeschke, Roger J, Davis
openaire +2 more sources