Results 91 to 100 of about 1,277,434 (275)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Cold Case Files of rAAV Capsid Influence on Transduction: New Leads
VirusesAdeno-associated virus (AAV) is a prevalent vector in viral gene therapy. Given its importance, significant efforts focus on engineering the capsid residues on the exterior surface to increase cell/tissue-specific binding to cellular receptors or to ...
Sara K. Powell
doaj +1 more source
Infection and Drug Resistance, 2021 James B Doub Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USACorrespondence: James B DoubDivision of Infectious Diseases, University of Maryland School of Medicine, 725 ...
Doub JB
doaj
The Apparatus of Belief: Prayer, Technology, and Ritual Gesture
Religions, 2016 Through a focus on the early history of a mass mediated ritual practice, this essay describes the “apparatus of belief,” or the specific ways in which individual religious belief has become intimately related to tele-technologies such as the radio.
Anderson Blanton
doaj +1 more source
Optomechanical transduction of an integrated silicon cantilever probe using a microdisk resonator
, 2010 Sensitive transduction of the motion of a microscale cantilever is central to many applications in mass, force, magnetic resonance, and displacement sensing.
Aksyuk, Vladimir +4 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Electroporation and the Transduction of Oligoarginines
, 2009 Certain short polycations, such as TAT and polyarginine, rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction as well as by endocytosis and macropinocytosis.
Alberts B +20 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Oxygen Signal Transduction [PDF]
IUBMB Life, 2001 AbstractAlthough manifestations of O 2 adaptation have long been examined, only now are biochemical mechanisms of O 2 regulation beginning to be understood. This article comments on the current state of knowledge about proteins that function as direct sensors of molecular oxygen and makes predictions about as yet undiscovered sensors.
openaire +2 more sources