Results 91 to 100 of about 70,628 (338)

Printed Interconnects for Heterogeneous Systems Integration on Flexible Substrates

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
Key components (sensors, energy devices, communication devices, computing chips, and interconnects) of flexible hybrid electronic (FHE) system connected via conductive printed metal tracks. The figure in the insets shows out‐of‐plane printed interconnects providing opportunities for lithography‐free formation of VIAs, in‐plane access of UTCs pads, and ...
Abhishek Singh Dahiya, Adamos Christou, Sihang Ma, Ravinder Dahiya   +3 more
wiley   +1 more source

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

Frontiers in Cellular Neuroscience, 2017
Background: During early prenatal stages of brain development, serotonin (5-HT)-specific neurons migrate through somal translocation to form the raphe nuclei and subsequently begin to project to their target regions.
Andrea Forero, Olga Rivero, Sina Wäldchen, Hsing-Ping Ku, Dominik P. Kiser, Yvonne Gärtner, Laura S. Pennington, Jonas Waider, Patricia Gaspar, Charline Jansch, Frank Edenhofer, Frank Edenhofer, Thérèse J. Resink, Robert Blum, Markus Sauer, Klaus-Peter Lesch, Klaus-Peter Lesch, Klaus-Peter Lesch   +17 more
doaj   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Four-color single-molecule imaging system for tracking GPCR dynamics with fluorescent HiBiT peptide

Biophysics and Physicobiology
Single-molecule imaging provides information on diffusion dynamics, oligomerization, and protein-protein interactions in living cells. To simultaneously monitor different types of proteins at the single-molecule level, orthogonal fluorescent labeling ...
Toshiki Yoda, Yasushi Sako, Asuka Inoue, Masataka Yanagawa   +3 more
doaj   +1 more source

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis

eLife, 2015
Little is known on post-transcriptional regulation of adult and embryonic stem cell maintenance and differentiation. Here we characterize the role of Ddb1, a component of the CUL4-DDB1 ubiquitin ligase complex.
Jie Gao, Shannon M Buckley, Luisa Cimmino, Maria Guillamot, Alexandros Strikoudis, Yong Cang, Stephen P Goff, Iannis Aifantis   +7 more
doaj   +1 more source

Simple Model of the Transduction of Cell-Penetrating Peptides

, 2010
Cell-penetrating peptides (CPPs) such as HIV's trans-activating transcriptional activator (TAT) and polyarginine rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction.
Andrews, Bevers, Chen, Datta, Dom, Duchardt, Fischer, Frankel, Grandmaison, Green, Haase, Harbour, Herce, Hosotani, Jiang, K. Cahill, Kuge, Lipinski, Mai, Melikov, Mendoza, O'Shaughnessy, Parsegian, Prochiantz, Rostovtseva, Rothbard, Rothbard, Saito, Snyder, Snyder, Stone, Tang, Tünnemann, Tünnemann, Tünnemann, Tyagi, Voelker, Wadia, Willam, Zhou, Ziegler   +40 more
core   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

Molecular principles underlying aggressive cancers

Signal Transduction and Targeted Therapy
Aggressive tumors pose ultra-challenges to drug resistance. Anti-cancer treatments are often unsuccessful, and single-cell technologies to rein drug resistance mechanisms are still fruitless.
Ruth Nussinov, Bengi Ruken Yavuz, Hyunbum Jang   +2 more
doaj   +1 more source

Non-Functional Trace Amine-Associated Receptor 1 Variants in Patients With Mental Disorders

Frontiers in Pharmacology, 2019
Background: The G protein–coupled receptor (GPCR) trace amine-associated receptor 1 (TAAR1) is expressed across brain areas involved in emotions, reward and cognition, and modulates monoaminergic and glutamatergic neurotransmissions.
Grazia Rutigliano, Grazia Rutigliano, Julia Bräunig, Claudia Del Grande, Vittoria Carnicelli, Isabella Masci, Sergio Merlino, Gunnar Kleinau, Luca Tessieri, Simone Pardossi, Sarah Paisdzior, Liliana Dell’Osso, Heike Biebermann, Riccardo Zucchi   +13 more
doaj   +1 more source