Results 111 to 120 of about 35,843 (287)

Survival intravascular photoacoustic imaging of lipid‐rich plaque in cholesterol fed rabbits

Translational Biophotonics, Volume 4, Issue 4, December 2022., 2022
Early identification of vulnerable plaques in vivo can have a positive impact on guiding the treatment of cardiovascular disease. In this work, Ji‐Xin Cheng and coworkers demonstrate survival intravascular photoacoustic imaging of lipid‐laden plaques in live cholesterol‐fed rabbits.
Yi Zhang, Erik Taylor, Nasi Huang, James Hamilton, Ji‐Xin Cheng   +4 more
wiley   +1 more source

Developing a new biophysical tool to combine magneto-optical tweezers with super-resolution fluorescence microscopy [PDF]

arXiv, 2015
We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and manipulation.
arxiv  

HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis

Cytoskeleton, EarlyView.
Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman, Faruk Şimşek, Aadil Javed, Kemal Sami Korkmaz   +3 more
wiley   +1 more source

Progress in COVID research and developments during pandemic

VIEW, Volume 3, Issue 6, December 2022., 2022
The pandemic respiratory disease COVID‐19 has spread over the globe within a small span of time. Generally, there are two important points are being highlighted and considered towards the successful diagnosis and treatment process. The first point includes the reduction of the rate of infections and the next one is the decrease of the death rate.
Sudheesh K. Shukla, Santanu Patra, Trupti R. Das, Dharmesh Kumar, Anshuman Mishra, Ashutosh Tiwari   +5 more
wiley   +1 more source

Protocol for live-cell Förster resonance energy transfer imaging to reveal the bistable insulin response of single C2C12-derived myotubes

STAR Protocols
Summary: Based on our hypothesis that myotubes exhibit a bistable response to insulin, here we present a protocol for finely measuring Akt phosphorylation in single myotubes under insulin stimulation.
Javed Akhtar, Muhammad Imran, Guanyu Wang   +2 more
doaj  

Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis

Cytoskeleton, EarlyView.
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai, Nicole C. Rodgers, Allen P. Liu   +2 more
wiley   +1 more source

Single‐cell/nanoparticle trajectories reveal two‐tier Lévy‐like interactions across bacterial swarms

VIEW, Volume 3, Issue 6, December 2022., 2022
Bacterial community is a typical model system to study the behavior of multicellular organization, how millions of cells are organized, and how they communicate efficiently microscopically on large spatiotemporal scales have attracted a lot of attention.
Yuqian Sang, Xiaodong Wen, Yan He
wiley   +1 more source

Canonical and non-canonical integrin-based adhesions dynamically interconvert

Nature Communications
Adhesions are critical for anchoring cells in their environment, as signaling platforms and for cell migration. In line with these diverse functions different types of cell-matrix adhesions have been described.
Fabian Lukas, Claudia Matthaeus, Tania López-Hernández, Ines Lahmann, Nicole Schultz, Martin Lehmann, Dmytro Puchkov, Jan Pielage, Volker Haucke, Tanja Maritzen   +9 more
doaj   +1 more source

Single‐Molecule Tracking and Super‐Resolution Microscopy Unveil Actin‐Driven Membrane Nanotopography Shaping Stable Integrin Adhesions in Developing Tissue

Cytoskeleton, EarlyView.
ABSTRACT Single molecule tracking and super‐resolution microscopy of integrin adhesion proteins and actin in developing Drosophila muscle attachment sites reveals that nanotopography triggered by Arp2/3‐dependent actin protrusions promotes stable adhesion formation.
Tianchi Chen, Cecilia H Fernández‐Espartero, Grégory Giannone   +2 more
wiley   +1 more source

Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy

WIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 1, January/February 2023., 2023
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa, Izadora Rossi, Mahamed Abdullahi, Marcel Ivan Ramirez, Dan Stratton, Jameel Malhador Inal   +5 more
wiley   +1 more source