Results 131 to 140 of about 34,099 (218)

Strategies for Assessing Post‐Wildfire Geomorphic Resilience in Semiarid Rivers

River Research and Applications, EarlyView.
ABSTRACT We review and summarize diverse components of a catchment that can be monitored after wildfire to assess the geomorphic resilience of the river corridor in semiarid regions. We distinguish upland portions of river catchments from river corridors.
Ellen Wohl, Shayla Triantafillou, Alex Thornton‐Dunwoody, Connor Mertz, Katie Larkin, William Keenan, Steven Griffin, Dylan Davis, Lindsey Blehm   +8 more
wiley   +1 more source

Tetrazine Functionalized Graphene Enables Capture of Ultra‐Low Concentrations of Biomacromolecules

Small, EarlyView.
A novel method for covalent modification of monolayer graphene utilizing tetrazine containing diazonium salt is demonstrated. The modified graphene bearing tetrazine moieties undergoes inverse electron demand Diels‐Alder reactions with trans‐cyclooctene‐linked molecules, enabling bioorthogonal attachment of nanobodies that selectively capture EGFP ...
Ravindra K. Gupta, Hanbin Jeong, April Goehring, Eric Gouaux, Maggie He   +4 more
wiley   +1 more source

With a little help from a friend - a new partner for acid-sensitive channels. [PDF]

Pflugers Arch
Roeper J.
europepmc   +1 more source

Organic Transistor‐Based Neuromorphic Electronics and Their Recent Applications

Small Methods, EarlyView.
This review highlights recent progress in organic neuromorphic electronics, showing how organic semiconductors enable synaptic and neuronal functions with low power, mechanical flexibility, and biocompatibility. By bridging materials, devices, and systems, organic platforms are accelerating brain‐inspired computing toward applications in artificial ...
Ziru Wang, Feng Yan
wiley   +1 more source

AAV-PHP.eB achieves superior neuronal transduction over AAV9 in pigtail macaques following intracerebroventricular administration. [PDF]

Mol Ther Methods Clin Dev
Fortuna MG, Nyberg LH, Taskin N, Hunker A, Weed N, Gudsnuk K, Berg M, Levi BP, Lein E, Ting JT.   +9 more
europepmc   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Editorial: Structure and mechanism of microbial membrane active transporters. [PDF]

Front Microbiol
Jiang X, Smallwood CR, Klebba PE, Bonaccorsi di Patti MC.   +3 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Influence of PLIN5 and lipid composition on lipid droplet contact sites with other organelles. [PDF]

Biochem Biophys Rep
Mohammadian M, Asfia S, Seemann R.
europepmc   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source