Results 141 to 150 of about 70,628 (338)

3P312 Effects of low-pass filter characteristics on temporal patterns of signal transduction(Mathematical biology,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Yu Toyoshima, Kazuhiro Fujita, Shinsuke Uda, Yuichi Ozaki, Hiroyuki Kubota, Shinya Kuroda   +5 more
openalex   +2 more sources

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

3P266 In situ photoirradiation solid state NMR study of local conformational change of Tyr174 corresponding to signal transduction in ppR(Photobiology: Vision & Photoreception,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Tetsurou Hidaka, Yuya Tomonaga, Izuru Kawamura, Takudo Nishio, Kazuhiro Osawa, Akimori Wada, Yuki Sudo, Naoki Kamo, Akira Naito   +8 more
openalex   +2 more sources

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

ChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone, Maria Rosaria Miranda, Francesca Di Matteo, Valeria Napolitano, Michela Aliberti, Simona Musella, Veronica Di Sarno, Gianluigi Lauro, Giuseppe Bifulco, Giacomo Pepe, Giovanna Aquino, Mario Felice Tecce, Isabel Maria Gomez‐Monterrey, Pietro Campiglia, Carmine Ostacolo, Alessia Bertamino, Vincenzo Vestuto, Tania Ciaglia   +17 more
wiley   +1 more source

1P081 Interactions between signal transduction proteins studied by surface force measurement(Protein:Function,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Taizo Umemura, Motoi Konishi, Miya Ishijima, Masaya Fujita, Kazue Kurihara   +4 more
openalex   +2 more sources

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

ChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean-François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

1P253 Inhibition mechanism of Interleukin-13 (IL-13) signal by extracellular region of Interleukin-13 receptor α2 chain (IL-13Rα2)(Biol & Artifi memb.:Signal transduction,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Fumiko Matsumoto, Takaaki Hatanaka, Taro Tamada, Eijiro Honjo, Shoichiro Ohta, Yuji Ito, Kenji Izuhara, Ryota Kuroki   +7 more
openalex   +2 more sources

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells [PDF]

, 2018
Attie, Alan D., Bernlohr, David A., Blaner, William S., Chen, Anping, Davidson, Nicholas O., Keller, Mark P., Lin, Jianguo, Newberry, Elizabeth P., Zheng, Shizhong   +8 more
core   +2 more sources

Broad‐Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders

ChemPhysChem, EarlyView.
Recent advancements in surface plasmon resonance protocols and simulations have enhanced the measurement and prediction of diffusion coefficients (D) for chemical species in microfluidic channels. These developments enable precise determination of D values for molecules ranging from a few angstroms to nanometric aggregates, facilitating detailed ...
Giuseppe Stefano Basile, Damiano Calcagno, Nunzio Tuccitto, Diego Sbardella, Giuseppe Grasso   +4 more
wiley   +1 more source

1P305 Propagation of noise in a signal transduction cascade and single-molecule measurement(Mathematical biology,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Naohiro Akuzawa, Tatsuo Shibata
openalex   +2 more sources