Results 151 to 160 of about 35,843 (287)

Cortactin: A universal host cytoskeletal target of Gram‐negative and Gram‐positive bacterial pathogens

open access: yesMolecular Microbiology, Volume 118, Issue 6, Page 623-636, December 2022., 2022
In host‐pathogen interactions, actin‐cytoskeletal dynamics play a crucial role in successful adherence, invasion, and intracellular motility by many intruding microbes. To achieve this goal, bacterial pathogens target major host regulators, one of which is the key actin‐binding protein and class‐II actin nucleation‐promoting factor cortactin.
Irshad Sharafutdinov   +4 more
wiley   +1 more source

Discovery, design, and engineering of enzymes based on molecular retrobiosynthesis

open access: yesmLife, EarlyView.
Abstract Biosynthesis—a process utilizing biological systems to synthesize chemical compounds—has emerged as a revolutionary solution to 21st‐century challenges due to its environmental sustainability, scalability, and high stereoselectivity and regioselectivity.
Ancheng Chen   +5 more
wiley   +1 more source

FtsH degrades kinetically stable dimers of cyclopropane fatty acid synthase via an internal degron

open access: yesMolecular Microbiology, Volume 119, Issue 1, Page 101-111, January 2023., 2023
The cellular proteome is in a constant state of flux, as changes in the environment necessitate rapid functional responses, often via mechanisms involving protein degradation. FtsH, a membrane‐bound AAA+ protease, degrades cyclopropane fatty acid synthase, an enzyme that is transiently upregulated upon entrance into stationary phase.
Sanjay B. Hari   +3 more
wiley   +1 more source

Current Advances in the Combination of Fatty Acids and Resveratrol to Fight Ocular Diseases

open access: yesMolecular Nutrition &Food Research, EarlyView.
Graphical abstract illustrating the effects of Resvega administration on choroidal neovascularization and resveratrol metabolism in the retina. The diagram illustrates that oral administration of Resvega leads to a decrease in choroidal neovascularization.
Dominique Delmas   +3 more
wiley   +1 more source

B-cell interleukin 1 receptor 1 modulates the female adipose tissue immune microenvironment during aging. [PDF]

open access: yesJ Leukoc Biol
Carey A   +6 more
europepmc   +1 more source

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