Results 161 to 170 of about 34,099 (218)

Protocol to track single-cell-derived clones using DNA barcoding combined with single-cell RNA sequencing. [PDF]

STAR Protoc
Shin HJ, Sharma S, Kronheim S, Cheung M, Nguyen LV.   +4 more
europepmc   +1 more source

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

Photochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee, Seo‐Hyeon Kim, Young Jin Kang, Il‐Kug Kim, Yun‐Jin Hwang, Du‐Hyong Cho   +5 more
wiley   +1 more source

Activation of the AKT-mTOR pathway confers selpercatinib resistance in thyroid cancer cells harboring the <i>CCDC6-RET</i> fusion gene. [PDF]

Biochem Biophys Rep
Amitani M, Shimizu T, Oba T, Kawamura M, Ito KI.   +4 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Methodological validation of a cryo-TEM-based detection method for empty capsid ratio in recombinant adeno-associated virus. [PDF]

Biochem Biophys Rep
Xu L, Chen J, Zhu W, Zhao Y, Zheng F, Du R, Jiang Y, Yang Y, Chen Y, Dong Y, Zhang Z, Tong Y.   +11 more
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Characterization of a novel <i>Phietavirus</i> genus bacteriophage and its potential for efficient transfer of modified shuttle plasmids to <i>Staphylococcus aureus</i> strains of different clonal complexes. [PDF]

Microbiol Spectr
Kałuski Ł, Stefańczyk E, Głowacka-Rutkowska A, Gawor J, Empel J, Orczykowska-Kotyna M, Szczypkowska A, Żuchniewicz K, Gromadka R, Łobocka M.   +9 more
europepmc   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Are viral vector-mediated therapies compatible with aberrant glycosylation? [PDF]

Mol Ther Methods Clin Dev
Muffels IJJ, Budhraja R, Radenkovic S, Shah R, Pandey A, Morava E, Kozicz T.   +6 more
europepmc   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source