Results 11 to 20 of about 411,981 (355)

Hybrid Quantum Mechanical/Molecular Mechanical Methods For Studying Energy Transduction in Biomolecular Machines.

open access: yesAnnual Review of Biophysics, 2022
Hybrid quantum mechanical/molecular mechanical (QM/MM) methods have become indispensable tools for the study of biomolecules. In this article, we briefly review the basic methodological details of QM/MM approaches and discuss their applications to ...
T. Kubař, M. Elstner, Q. Cui
semanticscholar   +1 more source

Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT

open access: yesGlobal Challenges, 2022
Oncological diseases have become the second leading cause of death from noncommunicable diseases worldwide and a major threat to human health. With the continuous progress in cancer research, the mechanical cues from the tumor microenvironment ...
Hao Tian   +4 more
semanticscholar   +1 more source

Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants

open access: yesFrontiers in Pharmacology, 2022
G-protein coupled receptors (GPCR) transduce extracellular stimuli into the cell interior and are thus centrally involved in almost all physiological-neuronal processes.
David Speck   +11 more
doaj   +1 more source

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting

open access: yesFrontiers in Endocrinology, 2022
In conjunction with the endothelin (ET) type A (ETAR) and type B (ETBR) receptors, angiotensin (AT) type 1 (AT1R) and type 2 (AT2R) receptors, are peptide-binding class A G-protein-coupled receptors (GPCRs) acting in a physiologically overlapping context.
David Speck   +8 more
doaj   +1 more source

Biophysical Principles of Ion-Channel-Mediated Mechanosensory Transduction [PDF]

open access: yesCell Reports, 2019
Recent rapid progress in the field of mechanobiology has been driven by novel emerging tools and methodologies and growing interest from different scientific disciplines. Specific progress has been made toward understanding how cell mechanics is linked to intracellular signaling and the regulation of gene expression in response to a variety of ...
Cox, Charles D.   +2 more
openaire   +4 more sources

Biophysical mechanisms of intracellular signaling (transduction) in higher plants

open access: yesProceedings of the National Academy of Sciences of Belarus, Biological Series, 2023
Three fundamental processes running in plant organisms under influence of environment (light, gravity) and key importance were considered. In the light case these are phytоchrome regulation and phototropism considering process is gravitropism. Phytochrome is responsible for regulatory reaction at the inhibition of which the plants cannot be normally ...
I. D. Volotovski   +2 more
openaire   +1 more source

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