Results 211 to 220 of about 35,843 (287)

The path to the G protein‐coupled receptor structural landscape: Major milestones and future directions

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel, Zeenat Zara, Alessandro Nicoli, Alexandra Steuer, Marta Lopez‐Balastegui, Jana Selent, Sanjai Karanth, Melanie Koehler, Antonella Ciancetta, Layara Akemi Abiko, Franz Hagn, Antonella Di Pizio   +11 more
wiley   +1 more source

Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis. [PDF]

Sci Rep
Lin C, Zheng S, Liu K, Yu R, Guan P, Hu B, Jiang L, Su M, Hu G, Chen Q, Zhang X.   +10 more
europepmc   +1 more source

1P-261 Role of tyrosine in the signal transduction from Sensory Rhodopsin I to the transducer for positive phototaxis(The 46th Annual Meeting of the Biophysical Society of Japan)

, 2008
Hazuki Takahashi, Yuji Furutani, Jun Sasaki, John L. Spudich, Hideki Kandori   +4 more
openalex   +2 more sources

A bio. tools collection of online resources for GPCR research

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors are highly complex signal transduction proteins with many potential biomedical applications. Researchers from different fields work together to improve mechanistic understanding of GPCR function and to transfer that knowledge in order to advance therapeutic options.
Tõnis Laasfeld, Friederike Wunsch, Avgi E. Apostolakou, Adrián García‐Recio, Gáspár Pándy‐Szekeres, Slawomir Filipek, Masha Y. Niv, Jana Selent, David E. Gloriam, Marcel Bermudez   +9 more
wiley   +1 more source

Editorial: Multi-targeted tyrosine kinase inhibitors in the treatment of cancer and neurodegenerative disorders. [PDF]

Front Chem
Sever B, Saso L, Tzoneva R, Onnis V, Ciftci H.   +4 more
europepmc   +1 more source

1S4-5 Interaction between Protein and Biomolecule Arising from Translational Motion of Water Molecules and Thermodynamic Quantities(1S4 Water as a key player in chemomechanical energy transduction: From ATP to Motility,The 46th Annual Meeting of the Biophysical Society of Japan)

, 2008
Ryo Akiyama
openalex   +2 more sources

Vestibular modulation by stimulant derivatives in a pentameric ligand‐gated ion channel

British Journal of Pharmacology, EarlyView.
Background and Purpose Allosteric modulation of pentameric ligand‐gated ion channels (pLGICs) are critical for the action of neurotransmitters and many psychoactive drugs. However, details of their modulatory mechanisms remain unclear, especially beyond the orthosteric neurotransmitter‐binding sites. The recently reported prokaryotic symbiont of Tevnia
Emelia Karlsson, Olivia Andén, Chen Fan, Zaineb Fourati, Ahmed Haouz, Yuxuan Zhuang, Rebecca J. Howard, Marc Delarue, Erik Lindahl   +8 more
wiley   +1 more source

"Forcing" new interpretations of molecular tension sensor studies. [PDF]

Cell Rep Methods
Pawlak MR, Smiley AT, Gordon WR.
europepmc   +1 more source

1S4-6 Roles of water in protein structure fluctuation and functioning(1S4 Water as a key player in chemomechanical energy transduction: From ATP to Motility,The 46th Annual Meeting of the Biophysical Society of Japan)

, 2008
Masaki Sasai
openalex   +2 more sources

Polyethylene Glycols Stimulate Ca²⁺ Signaling, Cytokine Production, and the Formation of Neutrophil Extracellular Traps. [PDF]

Int J Nanomedicine
Hinz A, Stankiewicz S, Litewka JJ, Ferdek PE, Sochalska M, Bzowska M.   +5 more
europepmc   +1 more source