ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq +6 more
wiley +1 more source
Mitochondrial calcium overload is the trigger for carbon monoxide neurotoxicity. [PDF]
Angelova PR +4 more
europepmc +1 more source
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Methodological validation of a cryo-TEM-based detection method for empty capsid ratio in recombinant adeno-associated virus. [PDF]
Xu L +11 more
europepmc +1 more source
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga +9 more
wiley +1 more source
Activation of the AKT-mTOR pathway confers selpercatinib resistance in thyroid cancer cells harboring the <i>CCDC6-RET</i> fusion gene. [PDF]
Amitani M +4 more
europepmc +1 more source
Organic Transistor‐Based Neuromorphic Electronics and Their Recent Applications
This review highlights recent progress in organic neuromorphic electronics, showing how organic semiconductors enable synaptic and neuronal functions with low power, mechanical flexibility, and biocompatibility. By bridging materials, devices, and systems, organic platforms are accelerating brain‐inspired computing toward applications in artificial ...
Ziru Wang, Feng Yan
wiley +1 more source
Characterization of a novel <i>Phietavirus</i> genus bacteriophage and its potential for efficient transfer of modified shuttle plasmids to <i>Staphylococcus aureus</i> strains of different clonal complexes. [PDF]
Kałuski Ł +9 more
europepmc +1 more source

