Results 41 to 50 of about 411,981 (355)
Acoustically tunable optical transmission through a subwavelength hole with a bubble [PDF]
, 2017 Efficient manipulation of light with sound in subwavelength-sized volumes is important for applications in photonics, phononics, and biophysics, but remains elusive.
Greentree, A, Maksymov, I
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Structural snapshot of a bacterial phytochrome in its functional intermediate state
Nature Communications, 2018 Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss ...
Andrea Schmidt +15 more
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Frontiers in Endocrinology, 2017 The thyroid-stimulating hormone receptor (TSHR) is a member of the glycoprotein hormone receptors, a sub-group of class A G-protein-coupled receptors (GPCRs).
Gerd Krause +7 more
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Binding, Thermodynamics, and Selectivity of a Non-peptide Antagonist to the Melanocortin-4 Receptor
Frontiers in Pharmacology, 2018 The melanocortin-4 receptor (MC4R) is a potential drug target for treatment of obesity, anxiety, depression, and sexual dysfunction. Crystal structures for MC4R are not yet available, which has hindered successful structure-based drug design.
Noureldin Saleh +11 more
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The Architectural Dynamics of the Bacterial Flagellar Motor Switch
Biomolecules, 2020 The rotary bacterial flagellar motor is remarkable in biochemistry for its highly synchronized operation and amplification during switching of rotation sense. The motor is part of the flagellar basal body, a complex multi-protein assembly.
Shahid Khan
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Communications Biology, 2021 Junfeng Chen et al. examine potential functional consequences of reproduction timing-associated TSHR alleles segregating in Atlantic herring. By comparing fish that spawn during the spring to those that spawn in the autumn, they find that the spring ...
Junfeng Chen +13 more
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Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]
, 2018 Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
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Frontiers in Endocrinology, 2019 The melanocortin-4 receptor (MC4R) can be endogenously activated by binding of melanocyte-stimulating hormones (MSH), which mediates anorexigenic effects. In contrast, the agouti-related peptide (AgRP) acts as an endogenous inverse agonist and suppresses
Nicolas Heyder +10 more
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