Results 61 to 70 of about 35,843 (287)
Advanced Materials, EarlyView.Wearable sensors, empowered by AI and smart materials, revolutionize healthcare by enabling intelligent disease diagnosis, personalized therapy, and seamless health monitoring without disrupting daily life. This review explores cutting‐edge advancements in smart materials and AI‐driven technologies that empower wearable sensors for diagnostics and ...
Shuwen Chen +14 more
wiley +1 more source
An Artificial Intelligent Signal Amplification System for in vivo Detection of miRNA
Frontiers in Bioengineering and Biotechnology, 2019 MicroRNAs (miRNA) have been identified as oncogenic drivers and tumor suppressors in every major cancer type. In this work, we design an artificial intelligent signal amplification (AISA) system including double-stranded SQ (S, signal strand; Q, quencher
Xibo Ma +22 more
doaj +1 more source
Transcriptional reprogramming by mutated IRF4 in lymphoma
Nature Communications, 2023 Disease-causing mutations in genes encoding transcription factors (TFs) can affect TF interactions with their cognate DNA-binding motifs. Whether and how TF mutations impact upon the binding to TF composite elements (CE) and the interaction with other ...
Nikolai Schleussner +45 more
doaj +1 more source
Nonextensive realizations in interacting ion channels: implications for mechano-electrical transducer mechanisms [PDF]
arXiv, 2022 Although there are theoretical studies on the thermodynamics of ion channels, an investigation involving the thermodynamics of coupled channels has not been proposed. To overcome this issue, we developed calculations to present a thermodynamic scenario associated with mechanoelectrical transduction channels as a single and coupling of two-state ...
arxiv
Transductive Rademacher Complexity and its Applications [PDF]
Journal Of Artificial Intelligence Research, Volume 35, pages
193-234, 2009, 2014 We develop a technique for deriving data-dependent error bounds for transductive learning algorithms based on transductive Rademacher complexity. Our technique is based on a novel general error bound for transduction in terms of transductive Rademacher complexity, together with a novel bounding technique for Rademacher averages for particular ...
arxiv +1 more source
Advanced Science, EarlyView.Extracellular matrix (ECM) viscoelasticity and spatial confinement regulate cellular processes such as cancer progression, yet their interplay remains poorly understood. By developing fibronectin (FN)‐micropatterned viscoelastic hydrogels mimicking breast cancer mechanics, this study explores breast epithelial cell mechanoresponse to ECM ...
Giuseppe Ciccone +6 more
wiley +1 more source
Retinal regions shape human and murine Müller cell proteome profile and functionality
Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023 Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan +15 more
wiley +1 more source
The NTD Nanoscope: potential applications and implementations
BMC Bioinformatics, 2011 Background Nanopore transduction detection (NTD) offers prospects for a number of highly sensitive and discriminative applications, including: (i) single nucleotide polymorphism (SNP) detection; (ii) targeted DNA re-sequencing; (iii) protein isoform ...
Horton-Chao Evenie +2 more
doaj +1 more source
Entropy, 2015 In performing their biological functions, molecular machines must process and transmit information with high fidelity. Information transmission requires dynamic coupling between the conformations of discrete structural components within the protein ...
Michael V. LeVine, Harel Weinstein
doaj +1 more source
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Advanced Science, EarlyView.Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang +5 more
wiley +1 more source