Results 81 to 90 of about 70,628 (338)

Collaborative online international learning (COIL): an engaging strategy for narrowing learning distances between two continents

open access: yesTürk Biyokimya Dergisi
Internationalization is a gold standard of higher education institutions ensuring students’ contact with different environments, including different languages and different cultures.
Cardoso Catarina   +3 more
doaj   +1 more source

Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]

open access: yes, 2018
Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
core   +1 more source

Bioactive Glass Microscaffolds Fabricated by Two‐Photon Lithography

open access: yesAdvanced Materials, EarlyView.
Microstructuring of bioactive glasses offers great potential to influence cell behavior for bone tissue engineering. By utilizing two‐photon lithography of a nanocomposite and thermal post‐processing, single‐micron features and complex structures are achieved.
Leonhard Hambitzer   +7 more
wiley   +1 more source

Sensory Transduction and Subjective Experience: Expression of eight genes in three senses suggests a radical model of consciousness [PDF]

open access: yes, 2007
Recent research into whole genome mapping of the mouse brain has made possible direct investigation of the brain expression of unusual genes. A search of the Allen Brain Atlas database has provided genetic and neuro-anatomical evidence for widespread ...
Chris C. King
core   +1 more source

Redox control of multidrug resistance and Its possible modulation by antioxidants [PDF]

open access: yes, 2016
Clinical efficacy of anticancer chemotherapies is dramatically hampered by multidrug resistance (MDR) dependent on inherited traits, acquired defence against toxins, and adaptive mechanisms mounting in tumours.
Cort, A.   +4 more
core   +3 more sources

Dual‐Selective Terahertz‐Nanodisc Metasurfaces for Exploring Neurotransmitter Dynamics beyond Spectral Limitations

open access: yesAdvanced Materials, EarlyView.
Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim   +6 more
wiley   +1 more source

Natural Design of a Stabilized Cross‐β Fold: Structure of the FuA FapC from Pseudomonas Sp. UK4 Reveals a Critical Role for Stacking of Imperfect Repeats

open access: yesAdvanced Materials, EarlyView.
We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang   +13 more
wiley   +1 more source

Finite-State Channel Models for Signal Transduction in Neural Systems

open access: yes, 2016
Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes.
Eckford, Andrew W.   +2 more
core   +1 more source

Leveraging Design of Experiments to Unravel the Amplification Mechanism of Single‐Molecule Wide‐Field Biosensors

open access: yesAdvanced Materials Interfaces, EarlyView.
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio   +9 more
wiley   +1 more source

On the origins of the compressive cochlear nonlinearity [PDF]

open access: yes, 2011
Various simple mathematical models of the dynamics of the organ of Corti in the mammalian cochlea are analysed. The models are assessed against their ability to explain the compressive nonlinear response of the basilar membrane.
Champneys, AR   +5 more
core  

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