Results 81 to 90 of about 411,981 (355)
Integrative Approaches for DNA Sequence‐Controlled Functional Materials
Advanced Functional Materials, EarlyView.DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo +4 more
wiley +1 more source
Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss
Frontiers in Aging Neuroscience, 2020 In the inner ear, cyclic guanosine monophosphate (cGMP) signaling has been described as facilitating otoprotection, which was previously observed through elevated cGMP levels achieved by phosphodiesterase 5 inhibition.
Philine Marchetta +14 more
doaj +1 more source
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]
, 2001 Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH +7 more
core +3 more sources
Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss
Advanced Healthcare Materials, EarlyView.Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan +8 more
wiley +1 more source
eLife, 2018 The endoplasmic reticulum (ER) supports biosynthesis of proteins with diverse transmembrane domain (TMD) lengths and hydrophobicity. Features in transmembrane domains such as charged residues in ion channels are often functionally important, but could ...
Matthew J Shurtleff +17 more
doaj +1 more source
Overshoot in biological systems modeled by Markov chains: a nonequilibrium dynamic phenomenon
, 2014 A number of biological systems can be modeled by Markov chains. Recently, there has been an increasing concern about when biological systems modeled by Markov chains will perform a dynamic phenomenon called overshoot.
Jia, Chen, Jiang, Daquan, Qian, Minping
core +1 more source
Energy integration describes sound-intensity coding in an insect auditory system [PDF]
, 2002 We investigate the transduction of sound stimuli into neural responses and focus on locust auditory receptor cells. As in other mechanosensory model systems, these neurons integrate acoustic inputs over a fairly broad frequency range.
Benda, Jan +3 more
core +2 more sources
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Advanced Healthcare Materials, EarlyView.Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source
STAR ProtocolsSummary: Based on our hypothesis that myotubes exhibit a bistable response to insulin, here we present a protocol for finely measuring Akt phosphorylation in single myotubes under insulin stimulation.
Javed Akhtar +2 more
doaj +1 more source
Engineering Biology, 2017 Retroactivity arises when the coupling of a molecular network [inline-formula] to a downstream network [inline-formula] results in signal propagation back from [inline-formula] to [inline-formula].
Abhishek Deshpande, Thomas E. Ouldridge
doaj +1 more source