Results 161 to 170 of about 145,799 (355)

Angiogenesis in rheumatoid arthritis: epidemiology, pathogenesis, signal transduction pathways, and nano-targeted therapeutic strategies

Universa Medicina
Angiogenesis is the formation of new blood vessels from existing vessels. In rheumatoid arthritis (RA), new blood vessels maintain a chronic inflammatory state by transporting inflammatory cells to the site of inflammation.
Joan Blin, Mohd Rohaizad Md Roduan, Roslida Abd Hamid   +2 more
doaj   +1 more source

Clofarabine Enhances the Transduction Efficiency of Recombinant AAV2 in the Retina

Investigative Ophthalmology & Visual Science
PURPOSE: Ribonucleotide reductase inhibitors, a class of antineoplastic agents, were investigated for their ability to enhance recombinant adeno-associated virus serotype 2 (rAAV2) transduction in the mouse retina and their underlying mechanisms.
Diao, Yuyao, Xiong, Xuewei, Liu, Jiayan, Teng, Xingbo, Shi, Qi, Jin, Shangli, Lei, Yahui, Ma, Shisi, Liu, Guei-Sheung, Liu, Lian, Yu, Guocheng, Wang, Jiang-Hui, Zhong, Jingxiang, Tu, Leilei   +13 more
openaire   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

194 A new highly potent transduction enhancer peptide to accelerate CAR-T production [PDF]

Aude-Marie Alem, Karsten Schnatbaum, Michael Drosch, Maren Eckey, Sebastian Pfeil, Pavlo Holenya, Holger Wenschuh, Aurlien Claeyssen   +7 more
openalex   +1 more source

Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation [PDF]

, 2002
Katharine A. Whartenby, Erin Straley, Hee‐Je Kim, Frederick Racke, Vivek Tanavde, Kevin Gorski, Linzhao Cheng, Drew M. Pardoll, Curt I. Civin   +8 more
openalex   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

CRISPR–Cas enhances HGT by transduction [PDF]

Nature Reviews Microbiology, 2018
openaire   +1 more source

Biosupercapacitors for Human‐Powered Electronics

Advanced Functional Materials, EarlyView.
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim, Seungho Baek, Woojung Jung, Hayeon Bae, Junyoung Mun, Yong Ho Kim, Sunkook Kim, Jung Ho Kim   +7 more
wiley   +1 more source

C-reactive protein mediated Fc-gamma-receptor signal transduction is enhanced by low density lipoprotein in human macrophages

, 2010
Kefei Li
openalex   +2 more sources

Microstructural Evolution Dominates the Changes in the Thermal Conductivity of Conjugated Polymers Upon Doping

Advanced Functional Materials, EarlyView.
The relationship between the doping induced microstructure and thermal conductivity changes is elucidated for conjugated polymers. Eight conjugated polymers with different doping systems are studied, showing varied thermal conductivity responses based on structural order.
Jiali Guo, Kai Xu, Jesika Asatryan, Matías Jesús Alonso‐Navarro, Osnat Zapata‐Arteaga, Mariavittoria Craighero, Aleksandr Perevedentsev, Renee Kroon, María Mar Ramos, José L. Segura, Jaime Martín, Christian Müller, Juan Sebastián Reparaz, Mariano Campoy‐Quiles   +13 more
wiley   +1 more source