Results 321 to 330 of about 145,799 (355)
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Enhanced chemi-mechanical transduction at nanostructured interfaces
Chemical Physics Letters, 2001Interfacial molecular recognition processes can be converted into mechanical responses via modulation of surface stress. We demonstrate dramatic enhancement in this transduction when quasi 3-D interfaces with nano-size features are used. Microcantelever surfaces are modified with gold nanospheres or granular films and functionalized with macrocycle ...
Nickolay V. Lavrik +3 more
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Enhancement of Retroviral Transduction by Cationic Liposomes
2003Publisher Summary This chapter discusses the enhancing effect of N-2,3-(dioleyloxy) propyl-N,N,N-trimethylammonium chloride (DOTMA) liposomes on HIV-1/infection, which is CD4-dependent. The complexation of retroviral vectors with cationic liposomes results in an increased transduction efficiency.
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Noise-enhanced energy transduction of molecular machinery
Chemical Physics Letters, 2002We have numerically investigated the enhance effect of noise on the energy transduction of molecular machinery. The energy transduction is enhanced with the increase of relative amplitude of the limit-cycle oscillation in polymer chain. And noise can enlarge the relative amplitude through a mechanism of stochastic resonance (SR). In the simulation, two
Zhiwei Wang, Zhonghuai Hou, Houwen Xin
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Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors
2022Adeno-associated viruses (AAV) are useful vectors for transducing cells in vitro and in vivo. Targeting of specific cell subsets with AAV is limited by the broad tropism of AAV serotypes. Nanobodies are single immunoglobulin variable domains from heavy chain antibodies that naturally occur in camelids.
Anna Marei, Mann +6 more
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Blockade of β-adrenoceptors enhances cAMP signal transduction in vivo
European Journal of Pharmacology, 1998The aim of this study was to determine whether the blockade of beta-adrenoceptors would enhance cAMP-mediated signal transduction processes in vivo. The administration of the membrane permeable cAMP analogue, 8-(4-chlorophenylthiol)-cAMP (8-CPT-cAMP, 10 micromol/kg, i.v.) produced an increase in heart rate (+27 +/- 2%, P < 0.05), a fall in mean ...
E J, Whalen, A K, Johnson, S J, Lewis
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Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo.
Cancer research, 2001The protein transduction domain (PTD) embedded in the HIV TAT protein (amino acids 47-57) has been shown to successfully mediate the introduction of heterologous peptides and proteins in excess of Mr 100,000 into mammalian cells in vitro and in vivo. We report here that the modeled structure of the TAT PTD is a strong amphipathic helix. On the basis of
A, Ho +4 more
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Polyethyleneimine-coating enhances adenoviral transduction of mesenchymal stem cells
Biochemical and Biophysical Research Communications, 2014Mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential, which makes them attractive targets for regenerative medicine applications. Efficient gene transfer into MSCs is essential for basic research in developmental biology and for therapeutic applications involving gene-modification in regenerative medicine.
Xinglei, Yao +9 more
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Enhanced transduction of dendritic cells by FcγRI‐targeted adenovirus vectors
The Journal of Gene Medicine, 2007AbstractBackgroundThe high affinity Fcγ receptor I (FcγRI; aka CD64) is expressed by dendritic cells (DC) and antigens targeted to this receptor elicit enhanced immune responses. This study was designed to test the hypothesis that targeting an adenoviral (Ad) vector to FcγRI would lead to enhanced transduction of DC and an improved immune response to ...
Ramil, Sapinoro +3 more
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Robustness Enhancement of Sensory Transduction by Hair Bundles
2018A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of ...
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2001
Hybrid microelectromechanical systems (MEMS) based on microcantilevers (MCs) that exhibit very large chemi-mechanical responses are described. The principle method for enhancing response involves introducing metallic nanostructure to one side of the MC. This serves to increase surface area and create new modes of analyte-induced surface stress. Methods
Michael J. Sepaniak +3 more
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Hybrid microelectromechanical systems (MEMS) based on microcantilevers (MCs) that exhibit very large chemi-mechanical responses are described. The principle method for enhancing response involves introducing metallic nanostructure to one side of the MC. This serves to increase surface area and create new modes of analyte-induced surface stress. Methods
Michael J. Sepaniak +3 more
openaire +1 more source