Results 151 to 160 of about 686,707 (295)

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection. [PDF]

open access: yesPLoS One
Galitsyna EV   +5 more
europepmc   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti   +10 more
wiley   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

open access: yesAdvanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz   +5 more
wiley   +1 more source

Preparation, characterization, and transfection efficiency of low molecular weight polyethylenimine-based nanoparticles for delivery of the plasmid encoding CD200 gene

open access: yes, 2017
Fatemeh Nouri,1 Hossein Sadeghpour,2 Reza Heidari,3 Ali Dehshahri,1,4,5 1Department of Pharmaceutical Biotechnology, 2Department of Medicinal Chemistry, 3Department of Pharmacology and Toxicology, School of Pharmacy, 4Center for Nanotechnology in Drug ...
Dehshahri A   +3 more
core  

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

open access: yesAdvanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi   +14 more
wiley   +1 more source

Factors influencing transfection efficiency of pIDUA/nanoemulsion complexes in a mucopolysaccharidosis type I murine model

open access: yes, 2017
Michelle Fraga,1,2 Talita Giacomet de Carvalho,2,3 Juliana Bidone,1 Roselena Silvestri Schuh,1,2 Ursula Matte,2,3 Helder Ferreira Teixeira1 1Pharmaceutical Sciences Graduate Program, Universidade Federal do Rio Grande do Sul, 2Gene Therapy Center ...
de Carvalho TG   +5 more
core  

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