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Viral and nonviral delivery systems for gene delivery
Advanced Biomedical Research, 2012 Gene therapy is the process of introducing foreign genomic materials into host cells to elicit a therapeutic benefit. Although initially the main focus of gene therapy was on special genetic disorders, now diverse diseases with different patterns of ...
Nouri Nayerossadat +2 more
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Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics
Journal of Nanotechnology, 2022 The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale +3 more
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Hybrid Membrane-Derived Nanoparticles for Isoliquiritin Enhanced Glioma Therapy
Pharmaceuticals, 2022 Due to the obstruction and heterogeneity of the blood-brain barrier, the clinical treatment of glioma has been extremely difficult. Isoliquiritigenin (ISL) exhibits antitumor effects, but its low solubility and bioavailability limit its application ...
Wenwan Shi +10 more
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Pharmaceutics, 2023 The overexpression of the human epidermal growth factor 2 (HER2/neu) oncogene is predictive of adverse breast cancer prognosis. Silencing the HER2/neu overexpression using siRNA may be an effective treatment strategy.
Adhika Balgobind +3 more
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Gene Delivery to the Airway [PDF]
Current Protocols in Human Genetics, 2013 AbstractThis unit describes generation of and gene transfer to several commonly used airway models. Isolation and transduction of primary airway epithelial cells are first described. Next, the preparation of polarized airway epithelial monolayers is outlined. Transduction of these polarized cells is also described.
Nicholas W, Keiser, John F, Engelhardt
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Molecules, 2021 Cancer-based magnetic theranostics has gained significant interest in recent years and can contribute as an influential archetype in the effective treatment of cancer.
Deevak Ramnandan +3 more
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Dendrimers as Modifiers of Inorganic Nanoparticles for Therapeutic Delivery in Cancer
Pharmaceutics, 2023 The formulation of nanoscale systems with well-defined sizes and shapes is of great interest in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are polymers that have attracted interest due to their size, shape, branching
Mkhuseli Zenze +2 more
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Nanomaterials, 2022 Cancer nanotherapeutics is an important field of research which utilizes nanomaterials as an approach to cancer therapy. Nano-mediated therapeutic delivery systems overcome the adverse side effects of traditional cancer treatment methods.
Jeaneen Venkatas +2 more
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Bimetallic nanoparticles as suitable nanocarriers in cancer therapy
Scientific African, 2023 Cancer is a widespread disease which has been prevalent for decades and for which a cure is yet to be discovered. Current treatments are fraught with severe side effects to patients and with no certainty of remission.
Haseena Makada +2 more
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Dendrimer-Coated Gold Nanoparticles for Efficient Folate-Targeted mRNA Delivery In Vitro
Pharmaceutics, 2021 Messenger RNA (mRNA) is not an attractive candidate for gene therapy due to its instability and has therefore received little attention. Recent studies show the advantage of mRNA over DNA, especially in cancer immunotherapy and vaccine development.
Londiwe Simphiwe Mbatha +3 more
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