Results 11 to 20 of about 4,269,896 (304)
Dendrimers in gene delivery [PDF]
Advanced Drug Delivery Reviews, 2005 Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also make these nanoscaled materials highly interesting for the development of synthetic (non-viral ...
Dufès, Christine +2 more
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Mannosylated liposomes for targeted gene delivery
International Journal of Nanomedicine, 2012 Fansheng Kong1, Fang Zhou1, Linfu Ge1, Ximin Liu1, Yong Wang21Department of Hematology, 2Department of Rehabilitation and Physiotherapy, General Hospital of Ji'nan Command, PLA, Ji'nan, People's Republic of ChinaBackground ...
Kong F, Zhou F, Ge L, Liu X, Wang Y.
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Brain Research Bulletin, 2010 This paper reviews the strategies of in vivo gene delivery to the cornea. A number of studies have demonstrated the feasibility of targeted delivery of oligonucleotides, small interfering RNA (siRNA), plasmid DNA, and viral vectors to the corneal cells in vivo, specifically stromal keratocytes and corneal epithelial cells, via intrastromal injection ...
Jinsong, Hao +3 more
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Gene delivery for immunoengineering
Current Opinion in Biotechnology, 2020 A growing number of gene delivery strategies are being employed for immunoengineering in applications ranging from infectious disease prevention to cancer therapy. Viral vectors tend to have high gene transfer capability but may be hampered by complications related to their intrinsic immunogenicity.
Sarah Y Neshat +2 more
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Fast-track applications : the potential for direct delivery of proteins and nucleic acids to plant cells for the discovery of the gene function. [PDF]
, 2005 In animal systems, several methods exist for the direct delivery of nucleic acids and proteins into cells for functional analysis. Until recently, these methods have not been applied to plant systems.
Roberts, Michael R.
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The magnetofection method: Using magnetic force to enhance gene delivery [PDF]
, 2003 In order to enhance and target gene delivery we have previously established a novel method, termed magnetofection, which uses magnetic force acting on gene vectors that are associated with magnetic particles.
Remy, J. (Jean-Serge) +17 more
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Journal of Nanobiotechnology, 2017 Background The cell source for transplantation therapy is always a prerequisite question to be solved in clinical applications. Neural cells are considered non-regenerable, which highly restrict their application in the treatment for nerve injury ...
Qingtong Yu +10 more
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Cold Spring Harbor Protocols, 2011 INTRODUCTIONModern cell biology increasingly relies on molecular tools to facilitate the study of cellular processes. With the advent of recombinant DNA technology, reverse transcription–polymerase chain reaction (RT-PCR) to amplify almost any gene, and fluorescent proteins that can be fused to any desired target protein, the number and scope of ...
David A, Dean, Joshua Z, Gasiorowski
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Characterization of Ku70(2)-NLS as bipartite nuclear localization sequence for non-viral gene delivery. [PDF]
, 2012 Several barriers have to be overcome in order to achieve gene expression in target cells, e.g. cellular uptake, endosomal release and translocation to the nucleus.
Maucksch, Christof +17 more
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Pharmaceutical Applications of Molecular Tweezers, Clefts and Clips
Molecules, 2019 Synthetic acyclic receptors, composed of two arms connected with a spacer enabling molecular recognition, have been intensively explored in host-guest chemistry in the past decades.
Amira Mbarek +2 more
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