Results 311 to 320 of about 968,391 (388)

Chronologically distributed transfection improves AAV2 and AAV2/8 capsid filling and reveals assembly schedule divergence. [PDF]

Mol Ther Methods Clin Dev
Chen Q, Lee CH, Whitfield R, Nesbeth DN.
europepmc   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Peste des petit ruminants viruses (PPRV) can escape RNA interference in vitro [PDF]

, 2010
Albina, Emmanuel, Holz, Carine, Keita, Djénéba, Kwiatek, Olivier, Libeau, Geneviève, Minet, Cécile, Nizamani, Zaheer Ahmed, Servan de Almeida, Renata   +7 more
core  

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Improved localized mRNA delivery using lipid nanoparticles with a novel synthetic cholesterol derivative.

RSC Pharm
Sahel DK, Renner J, Vlasova KY, Pennock ND, Haque ST, Jozic A, Walker JM, Sun C, Sahay G.   +8 more
europepmc   +1 more source

Downregulation of Gene Expression by Alpha Satellite Transcripts. [PDF]

Int J Mol Sci
Ljubić S, Matulić M, Đermić D, Feliciello MC, Procino A, Passaro F, Ugarković Đ, Feliciello I.   +7 more
europepmc   +1 more source

Optimization of Gene Transfection in Murine Myeloma Cell Lines using Different Transfection Reagents.

, 2010
Mahdi Shabani, Shayda Hemmati, Reza Hadavi, Zahra Amirghofran, Mahmood Jeddi‐Tehrani, Hodjattallah Rabbani, Fazel Shokri   +6 more
openalex   +1 more source