Results 81 to 90 of about 568,858 (297)

Associação entre proteínas do plasma seminal, motilidade e viabilidade espermática em coelhos submetidos a doping genético Association among seminal plasma proteins, sperm motility and sperm viability in rabbits submitted to gene doping

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Neste trabalho foi estudada a correlação entre o perfil proteico do plasma seminal e a motilidade e viabilidade espermática em coelhos submetidos ao tratamento com vetores de expressão contendo o gene da eritropoetina (EPO) e com EPO recombinante humana.
G Urtiaga, V.F Campos, T.F Collares, P.M.M Leon, J.C Deschamps, F.K Seixas, T Collares   +6 more
doaj  

Source of the Nonlinear Dependence of Bacteriophage SP82 Transfection on Deoxyribonucleic Acid Concentration [PDF]

, 1971
Herman T. Epstein
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Optimization of transfection of green fluorescent protein in pursuing mesenchymal stem cells in vivo

Turkish Journal of Hematology, 2008
OBJECTIVE: Green Fluorescent Protein (GFP) has been used as a marker of gene expression and a single cell marker in living organisms in cell biology studies.
Pınar Elçi, Meral Sarper, Ferit Avcu, Ali Uğur Ural, Yusuf Baran, Aysel Pekel   +5 more
doaj  

Transfection of Escherichia coli and Salmonella typhimurium Spheroplasts: Host-Controlled Restriction of Infective Bacteriophage P22 Deoxyribonucleic Acid [PDF]

, 1971
Rolf Benzinger, Ingrid Kleber
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Chitosan-Based Polymeric Nanoparticles as an Efficient Gene Delivery System to Cross Blood Brain Barrier: In Vitro and In Vivo Evaluations

Pharmaceuticals
Significant progress has been made in the field of gene therapy, but effective treatments for brain tumors remain challenging due to their complex nature.
Ishaq N. Khan, Shiza Navaid, Walifa Waqar, Deema Hussein, Najeeb Ullah, Muhammad Umar Aslam Khan, Zakir Hussain, Aneela Javed   +7 more
doaj   +1 more source

Factors Affecting Transfection in Bacillus stearothermophilus [PDF]

, 1971
Uldis N. Streips, N. E. Welker
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Comprehensive Comparison of Baculoviral and Plasmid Gene Delivery in Mammalian Cells

Viruses
(1) Recombinant protein production in mammalian cells is either based on transient transfection processes, often inefficient and underlying high batch-to-batch variability, or on laborious generation of stable cell lines.
Maria Toth, Manuel Reithofer, Gregory Dutra, Patricia Pereira Aguilar, Astrid Dürauer, Reingard Grabherr   +5 more
doaj   +1 more source