Results 91 to 100 of about 1,075,529 (290)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Numerical/Laplace transform analysis for MHD radiating heat/mass transport in a Darcian porous regime bounded by an oscillating vertical surface

Alexandria Engineering Journal, 2015
Analytical and numerical solutions of a non-linear MHD flow with heat and mass transfer characteristics of an incompressible, viscous, electrically conducting and Boussinesq’s fluid over a vertical oscillating plate embedded in a Darcian porous medium in
Sahin Ahmed, Abdul Batin, A.J. Chamkha
doaj   +1 more source

GAP: Genetic Algorithm Based Large-Scale Graph Partition in Heterogeneous Cluster

IEEE Access, 2020
Graph is an important model to describe various networks, and its scale becomes larger and larger with the development of communication and information technology.
Menghan Li, Huanqing Cui, Chuanai Zhou, Shaohua Xu   +3 more
doaj   +1 more source

Fog Computing in Medical Internet-of-Things: Architecture, Implementation, and Applications

, 2017
In the era when the market segment of Internet of Things (IoT) tops the chart in various business reports, it is apparently envisioned that the field of medicine expects to gain a large benefit from the explosion of wearables and internet-connected ...
Abtahi, Mohammadreza, Akbar, Umer, Borthakur, Debanjan, Constant, Nicholas, Dubey, Harishchandra, Mahler, Leslie, Mankodiya, Kunal, Monteiro, Admir, Sun, Yan, Yang, Qing   +9 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Remote Entanglement Generation Via Enhanced Quantum State Transfer

PRX Quantum
Achieving robust and scalable remote quantum entanglement is one of the fundamental challenges for the development of distributed quantum networks and modular quantum computing systems.
Tian-Le Wang, Peng Wang, Ze-An Zhao, Sheng Zhang, Ren-Ze Zhao, Xiao-Yan Yang, Hai-Feng Zhang, Zhi-Fei Li, Yuan Wu, Liang-Liang Guo, Yong Chen, Hao-Ran Tao, Lei Du, Chi Zhang, Zhi-Long Jia, Wei-Cheng Kong, Peng Duan, Ming Gong, Guo-Ping Guo   +18 more
doaj   +1 more source

A Randomized Proper Orthogonal Decomposition Method for Reducing Large Linear Systems [PDF]

, 2015
The proper orthogonal decomposition (POD) method is a powerful tool for reducing large data systems which can quickly overwhelm modern computing tools. In this thesis we provide a link between randomized projections and statistical methods by introducing
Marvin, Brad
core  

HEP@Home - A distributed computing system based on BOINC

, 2004
Project SETI@HOME has proven to be one of the biggest successes of distributed computing during the last years. With a quite simple approach SETI manages to process large volumes of data using a vast amount of distributed computer power.
Amorim, Antonio, Andrade, Pedro, Villate, Jaime   +2 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source