Results 91 to 100 of about 3,668,573 (294)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Explaining the variation in ¹³⁷Cs aggregated transfer factor for wild edible plants as a case study on Koshiabura (Eleutherococcus sciadophylloides) buds. [PDF]

Sci Rep, 2023
Hayashi S, Watanabe M, Kanao Koshikawa M, Takada M, Takechi S, Takagi M, Sakai M, Tamaoki M.   +7 more
europepmc   +1 more source

CoB/Ni-Based Multilayer Nanowire with High-Speed Domain Wall Motion under Low Current Control

, 2012
The spin-transfer torque motion of magnetic domain walls (DWs) in a CoB/Ni-based nanowire driven by a low current density of (1.12\pm0.8)\times10^{11} A m^{-2} has been observed indirectly by magnetotransport measurements.
Awano, Hiroyuki, Ngo, Duc-The, Watanabe, Norihito   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Permeability as an important parameter for radon risk classification of foundation soils

Annals of Geophysics, 2005
Permeability of soils and rocks for gases is one of the main parameters for final radon risk classification of building sites. For the improvement of the method for radon risk classification it is recommended to complete in situ measurements of
M. Neznal, M. Neznal
doaj   +1 more source

Gamma spectroscopy study of soil-plant transfer factor characteristics of ⁴⁰K, ²³²Th and ²²⁶Ra in some crops cultivated in southwestern region of Nigeria. [PDF]

Heliyon, 2023
Oladele BB, Ugbede FO, Arogunjo AM, Ajayi OS, Pereira A.   +4 more
europepmc   +1 more source

Cross-correlation trajectory study of V-V energy transfer in HF-HF and DF-DF [PDF]

, 1980
Results of a fully three‐dimensional classical trajectory calculation of vibrational energy transfer are presented for the collision of HF(v=1) with HF(v=1) and its deuterium analog.
Coltrin, M. E., Koszykowski, M. L., Marcus, R. A.   +2 more
core  

Recent and Future Measurements of the Neutron Electric Form Factor

, 2010
I review recently conducted measurements of $\gen$ as well as precision form factor experiments at high momentum transfer that will be performed with the 11 GeV electron beam at Jefferson Lab.Comment: Submitted to the XIII International Conference on ...
Semenov, Andrei
core   +1 more source