Results 131 to 140 of about 3,668,573 (294)

Forced convection and flow boiling with and without enhancement devices for top-side-heated horizontal channels [PDF]

open access: yes
The effect of enhancement devices on flow boiling heat transfer in coolant channels, which are heated either from the top side or uniformly was studied.
Boyd, Ronald D., Sr., Turknett, Jerry C.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

ASSIMILATION OF 134Cs FROM CONTAMINATED SOIL INTO CULTIVARS OF TRITICALE AND OATS [PDF]

open access: yesJournal of Central European Agriculture, 2007
Pot experiments with different triticale and oats varieties spread in Bulgaria were carried out. Three varieties of triticale (Rakita, TC-210, AD-7291) and three varieties of oats (Obrazcov chifl ik, W-!6 and W-17) were analized. The plants were grown on
TZ BINEVA, D STANEVA, I YORDANOVA
doaj  

Studies on Resistance Transfer Factors

open access: yesPathobiology, 1967
The presence of infective R factors in a high proportion of multiple resistant wild Enterobacteriaceae isolated from the faecal flora of Greek patients is demonstrated. Frequencies of transfer exceeding 1 × 10−2 per recipient cell were found in most crosses of non pathogenic × pathogenic Enterobacteriaceae studied, and vice versa.
openaire   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Transfer of Pollution Abatement Technology and Unemployment [PDF]

open access: yes
This paper investigates the effects of the transfer of pollution abatement technology on the level of urban unemployment, the total amount of pollution, and social welfare in a small, open Harris Todaro economy.
Muneyuki Saito, Yasuyuki Sugiyama
core  

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