Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Protein Electron Transfer in Solution, Protein Powders, and Electrode Confinement. [PDF]
Mostajabi Sarhangi S, Matyushov DV.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Resonance suppression method for single-phase LCL Grid-tied inverter based on active damping superposition. [PDF]
Dongdong C, Li M, Shengqi Z, Nuan W.
europepmc +1 more source
A Clinically Applicable Nomogram for Live Birth Prediction After IVF: The Zubeyde Hanim Model. [PDF]
Karaçin P +5 more
europepmc +1 more source
Transcription factor SPI1 drives immunosuppressive CD45<sup>+</sup> erythroid progenitor cells to ameliorate rheumatoid arthritis. [PDF]
Zhu WH +5 more
europepmc +1 more source
Astrocytic mitochondrial transfer: a new horizon for metabolic rescue and precision therapy in ischemic stroke. [PDF]
Lan X +12 more
europepmc +1 more source
Enhancing heat and mass transfer in hybrid nanofluid with gyrotactic microbes and local thermal non equlibrium effects using artificial neural network. [PDF]
Aoudia M +4 more
europepmc +1 more source
Discrete thermal analysis of the E-type shell-and-tube heat exchanger. [PDF]
Bayramoğlu K, Kaya I, Ust Y.
europepmc +1 more source

