Results 81 to 90 of about 3,668,573 (294)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Bioavailability of Cadmium and Nickel to Daucus carota L. and Corchorus olitorius L. treated by Compost and Microorganisms

Soil & Environment, 2017
The research work investigates the impact of the interaction between several rates of compost and microorganisms (bacteria, fungi, mycorrhiza) and their residual effects on growth and metals (Cd and Ni) uptake in carrot (Daucus carota L.) and jew´s ...
Mohamed Mahmoud Mohamed Ahmed, Mohamed Bahy-El-Din Mazen, Nivien Allam Nafady, Omaima Abdel Monsef   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Pion radiative weak decay from the instanton vacuum

, 2017
We investigate the vector and axial-vector form factors for the pion radiative weak decays $\pi^+\to e^+\nu_e \gamma$ and $\pi^+\to e^+\nu_e e^+ e^-$, based on the gauged effective chiral action from the instanton vacuum in the large $N_c$ limit.
Kim, Hyun-Chul, Shim, Sang-In
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

$\pi^0\to\gamma^*\gamma$ transition form factor within Light Front Quark Model

, 2012
We study the transition form factor of $\pi^0\to\gamma^* \gamma$ as a function of the momentum transfer $Q^2$ within the light-front quark model (LFQM). We compare our result with the experimental data by BaBar as well as other calculations based on the ...
Chao-Qiang Geng, Chong-Chung Lih, H. J. Behrend, J. P. B. C. de Melo, V. L. Chernyak   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Transfer Factor of Heavy Metals from Sediments to Organs of Mud Crabs (Scylla serrata) of Mida-Creek, Kilifi Kenya

Indonesian Journal of Innovation and Applied Sciences
Heavy metal accumulation and transfer from sediments to edible mud crab organs (Scylla serrata) pose major ecological and health risks to consumers. The bioaccumulation of these metals are detrimental if they are extremely toxic.
Emily Akinyi Ochieng, Fredrick Kayusi
doaj   +1 more source

Transfer Factors: Identification of Conserved Sequences in Transfer Factor Molecules [PDF]

Molecular Medicine, 2000
Transfer factors are small proteins that "transfer" the ability to express cell-mediated immunity from immune donors to non-immune recipients. We developed a process for purifying specific transfer factors to apparent homogeneity. This allowed us to separate individual transfer factors from mixtures containing several transfer factors and to ...
openaire   +2 more sources