Results 141 to 150 of about 17,573,077 (386)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Bootstrapped Oblivious Transfer and Secure Two-Party Function Computation [PDF]
, 2009 Ye Wang, Prakash Ishwar
openalex +1 more source
Head-related transfer functions of rabbits within the front horizontal plane [PDF]
, 2023 Mitchell L. Day
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On mechanisms for transfer using landmark value functions in multi-task lifelong reinforcement learning [PDF]
, 2019 Nick Denis
openalex +1 more source
P31: Antigenic target, antibody subclass, function and glycans and SARS‐CoV‐2 coinfection impact the placental transfer of herpes simplex virus antibodies [PDF]
, 2022 openalex +1 more source
The influence of a wall function on turbine blade heat transfer prediction [PDF]
The second phase of a continuing investigation to improve the prediction of turbine blade heat transfer coefficients was completed. The present study specifically investigated how a numeric wall function in the turbulence model of a two-dimensional ...
Whitaker, Kevin W.
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Random Channel Generator for Indoor Power Line Communication
Measurement Science Review, 2013 The paper deals with creating an indoor power line model based on random parameters. This model approximates the real parameters of the power line communication with sufficient precision.
Mlynek P., Misurec J., Koutny M.
doaj +1 more source