Results 171 to 180 of about 8,378,733 (308)

ASCT: a pipeline for standardized analysis of MEG/EEG directional connectivity. Practical guidelines for applications of source-based Directed Transfer Function. [PDF]

Front Neuroinform
Wyczesany M, Spadone S, Górski T, Łabaza A, Domagala M, Kaminski M, Ligeza TS, Capotosto P, Kroker T, Junghöfer M, Della Penna S.   +10 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Middle Ear Transfer Function in Acromegaly Patients. [PDF]

J Int Adv Otol
Bayindir E, Aslantas E, Can B, Slipcevic B, Celik S, Mutlu B, Kalcioglu MT.   +6 more
europepmc   +1 more source

Fluorescent Probes with Förster Resonance Energy Transfer Function for Monitoring the Gelation and Formation of Nanoparticles Based on Chitosan Copolymers. [PDF]

J Funct Biomater, 2023
Zlotnikov ID, Savchenko IV, Kudryashova EV.   +2 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

EEG-based network dynamics in cannabis and polydrug use: a directed transfer function approach. [PDF]

Psychopharmacology (Berl)
Binkowska AA, Kaszyńska A, Kamiński M, Blinowska K, Czarny J, Raczkowski M, Brzezicka A.   +6 more
europepmc   +1 more source

Simulation Analysis on the Performance of a Circular-Edge Technique in Measurements of the Modulation Transfer Function. [PDF]

J Med Phys, 2023
Maruyama S.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Time-frequency machine learning transfer function for central pressure waveforms. [PDF]

Eur Heart J Open
Niroumandi S, Wei H, Amlani F, Gorji H, Alavi R, Chirinos JA, Pahlevan NM.   +6 more
europepmc   +1 more source

The Cluster Transfer Function of AtNEET Supports the Ferredoxin-Thioredoxin Network of Plant Cells. [PDF]

Antioxidants (Basel), 2022
Zandalinas SI, Song L, Nechushtai R, Mendoza-Cozatl DG, Mittler R.   +4 more
europepmc   +1 more source