Results 171 to 180 of about 4,251,800 (292)

Assessment of cerebrovascular function in patients with sickle cell disease using transfer function analysis. [PDF]

open access: yesPhysiol Rep, 2022
Sayin ES   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Transfer Function of a Time-Varying Control System Considering Actuator Inertia

open access: yesChallenges and Issues of Modern Science
Purpose. Methodological support for building an algorithm for determining the transfer function (TF) of a link, which, considering the actuator dynamics and the disturbed motion of the mass center, is equivalent on a selected trajectory section to a ...
Volt Avdieiev
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Continuous wavelet based transfer function analysis of cerebral autoregulation dynamics for neuromonitoring using near-infrared spectroscopy. [PDF]

open access: yesFront Physiol
Thudium M   +12 more
europepmc   +1 more source

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