Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Transfer function matrix synthesis of two-dimensional systems [PDF]
, 1980 Paraskevopoulos, P
core +1 more source
Interpreting Modulation Transfer Function in Endoscopic Imaging: Spatial-Frequency Conversion Across Imaging Spaces and the Digital Image Domain with Case Studies. [PDF]
Sensors (Basel)Wang Q.
europepmc +1 more source
Point-Counterpoint: Transfer function analysis of dynamic cerebral autoregulation: To band or not to band? [PDF]
J Cereb Blood Flow Metab, 2023 Liu J, Simpson DM, Panerai RB.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Gray Markets and Multinational Transfer Pricing [PDF]
Gray markets arise when a manufacturer's products are sold outside of its authorized channels, for instance when goods designated for a foreign market are resold domestically.
Francesco Bova, Romana L. Autrey
core
Automated Task-Transfer Function Measurement for CT Image Quality Assessment Based on AAPM TG 233. [PDF]
J ImagingAnam C +7 more
europepmc +1 more source
Assessment of cerebrovascular function in patients with sickle cell disease using transfer function analysis. [PDF]
Physiol Rep, 2022 Sayin ES +6 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Assessing the Relative Performance of U.K. University Technology Transfer Offices: Parametric and Non-Parametric Evidence [PDF]
We present evidence on the relative efficiency of U.K. university technology transfer offices (TTOs) using data envelopment analysis (DEA) and stochastic frontier estimation (SFE). We find that U.K.
Mike Wright +3 more
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