Results 251 to 260 of about 17,526,649 (388)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Machine-to-Machine Transfer Function in Deep Learning-Based Quantitative Ultrasound. [PDF]

IEEE Trans Ultrason Ferroelectr Freq Control
Soylu U, Oelze ML.
europepmc   +1 more source

Transfer-function-free technique for the noninvasive determination of the human arterial pressure waveform. [PDF]

Physiol Rep, 2021
Giudici A, Palombo C, Morizzo C, Kozakova M, Cruickshank JK, Wilkinson IB, Khir AW.   +6 more
europepmc   +1 more source

Predictive modeling of seismic wave fields: Learning the transfer function using encoder-decoder networks

Jana Klinge, Sven Schippkus, Jan Walda, Céline Hadziioannou, Dirk Gajewski   +4 more
openalex   +2 more sources

Advancing the scale of synthetic biology via cross-species transfer of cellular functions enabled by iModulon engraftment [PDF]

Donghui Choe, Connor A. Olson, Richard Szubin, Hannah Yang, Jaemin Sung, Adam M. Feist, Bernhard Ø. Palsson   +6 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A transfer function based on bilinear transformation for narrow-band seismic record. [PDF]

PLoS One
Xu Z, Bai Y.
europepmc   +1 more source

DNA Methylation and Its Basic Function

Neuropsychopharmacology, 2013
Lisa D. Moore, Thuc M. Le, G. Fan
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Can processed images be used to determine the modulation transfer function and detective quantum efficiency? [PDF]

J Med Imaging (Bellingham)
Garland LM, Yang HJ, Picot PA, Tanguay J, Cunningham IA.   +4 more
europepmc   +1 more source