Results 41 to 50 of about 12,810,823 (193)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Description of Hot Compressive Stress-Strain Curves Using Transfer Functions

open access: yesMetals, 2019
Mathematical descriptions of true stress/true strain curves, experimentally obtained on cylindrical specimens under hot compressive conditions, are of great importance and are widely investigated. An additional black-box modelling approach using transfer
Franci Vode   +4 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

A formula for the mean human optical modulation transfer function as a function of pupil size.

open access: yesJournal of Vision, 2013
We have constructed an analytic formula for the mean radial modulation transfer function of the best-corrected human eye as a function of pupil diameter, based on previously collected wave front aberrations from 200 eyes (Thibos, Hong, Bradley, & Cheng ...
A. Watson
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Development of the PSO method for the determination of the dynamic response of a pyroelectric sensor

open access: yesInternational Journal of Metrology and Quality Engineering, 2016
We modeled a pyroelectric sensor by a current source connected in parallel with output impedance. The dynamic behavior of the sensor is described using a transfer function designed using the MATLAB Simulink environment.
Raouadi M.H., Sifi N., Touayar O.
doaj   +1 more source

Fast Multi-Objective Optimization of Multi-Parameter Antenna Structures Based on Improved BPNN Surrogate Model

open access: yesIEEE Access, 2019
In this paper, a surrogate model based on a sparsely connected back propagation neural networks (SC-BPNN) is proposed to reduce the large computational cost of conventional multi-objective antenna optimization problems.
Jian Dong, Wenwen Qin, Meng Wang
doaj   +1 more source

Experimental and Analytical Study of Secondary Path Transfer Function in Active Hydraulic Mount with Solenoid Actuator

open access: yesActuators, 2021
The active hydraulic mount with solenoid actuator (AHM-SNA) does not require permanent magnets, is of low cost, and has attracted wide attention. This paper focuses on each link of the secondary path in AHM-SNA, the transfer functions (TFs) were studied ...
Rang-Lin Fan   +4 more
doaj   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

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