Results 51 to 60 of about 166,250,325 (252)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]

open access: yes, 1971
The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Transfer of Training: A Reorganized Review on Work Environment and Motivation to Transfer [PDF]

open access: yesInternational Journal of Management, Knowledge and Learning, 2015
Effective application of skills & knowledge gained from a training program to a job situation, i.e. transfer of training, has become a great concern in training issues.
Imran Khan   +2 more
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Report of online regional training course on onboard fishing handling

open access: yes, 2022
This report is a part of an online regional training course on Onboard Fish Handling organized through the Zoom platform under the situation of the Coronavirus- 2019 (COVID-19) pandemic in the Southeast Asian region and all over the world.

core  

Annual report (Online); Other title: Title from file name: OPOTA annual report

open access: yes
Annual; Report for 2008 covers the calendar year; report for 2009 not published; report for 2010- covers the state fiscal year (July-June)
Ohio Peace Officer Training Commission.
core   +6 more sources

Transfer of training in alphabet arithmetic [PDF]

open access: yesMemory & Cognition, 2016
In recent years, several researchers have proposed that skilled adults may solve single-digit addition problems (e.g., 3 + 1 = 4, 4 + 3 = 7) using a fast counting procedure. Practicing a procedure, however, often leads to transfer of learning to unpracticed items; consequently, the fast counting theory was potentially challenged by subsequent studies ...
Jamie I D, Campbell   +3 more
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Efficiency of Ferritin bio-nanomaterial in reducing the pollutants level of water in the underground corridors of metro rail using GIS

open access: yesScientific Reports, 2022
The underground developments are likely to deteriorate the water quality, which causes damage to the structure. The pollutant levels largely affect the aquifer properties and alter the characteristics of the water quality.
R. Lilly   +8 more
doaj   +1 more source

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