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The structures and functions of transfer RNA

open access: bronzeProgress in Biophysics and Molecular Biology, 1978
Publisher Summary Transfer ribonucleic acid (tRNA) is the term used to describe a group of low molecular weight RNA molecules that play a vital part in protein synthesis Transfer RNAs were assigned the role of adaptor molecules by Hoagland et al.
J.P. Goddard
openalex   +4 more sources

Bacterial transfer RNAs [PDF]

open access: yesFEMS Microbiology Reviews, 2015
Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
openaire   +4 more sources

Transfer RNA and Origins of RNA Interference [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Almost 30 years ago the first microRNA (miRNA) was detected (Lee et al., 1993), later put in mechanistical context by the discovery of the RNA interference (RNAi) and RNA-induced silencing complex (RISC). miRNA is the variable RISC element (guide) that recognizes messenger RNA (mRNA) targets in the RNAi process facilitated by Argonaute (Ago) proteins ...
openaire   +5 more sources

Transfer RNA and human disease [PDF]

open access: yesFrontiers in Genetics, 2014
Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and result in very complicated clinical phenotypes. Mitochondrial tRNA (mt-tRNA) genes are "hotspots" for pathological mutations and over 200 mt-tRNA mutations have been linked to various disease states. Often these mutations prevent tRNA aminoacylation.
Susan M. Robey-Bond   +2 more
openaire   +3 more sources

Evolution of the Transfer RNA Molecule Evolution of the Transfer RNA Molecule

open access: yesZeitschrift für Naturforschung C, 1977
Abstract Base sequences of many transfer RNA (tRNA) species obtained from different sources contain homologous regions. These homologies, which are 6 to 20 nucleotides long, occur both within the same tRNA molecule and between many different tRNA molecules repeatedly.
Larry D. Greller   +2 more
openaire   +3 more sources

Transfer RNA comes of age [PDF]

open access: yesRNA, 2015
The year the journal RNA was founded was slated by some in scientific publishing to be the year that one particular type of RNA's run in the spotlight would end. In 1995 I had recently started as a post-doc with Dieter Soll at Yale when he came into the lab to solemnly inform us all that an editor at a certain (S)cience journal had just told him “we ...
openaire   +4 more sources

Structural organization of complexes of transfer RNAs with aminoacyl transfer RNA synthetases

open access: yesNucleic Acids Research, 1977
A variety of experimental data on synthetase-tRNA interactions are examined. Although these data previously had no direct explanation when viewed only in terms of the tRNA cloverleaf diagram, they can be rationalized according to a simple proposal that takes account of the three dimensional structure of tRNA.
Paul Schimmel, Alexander Rich
openaire   +4 more sources

Transfer RNA coded by the T4 bacteriophage genome. [PDF]

open access: green, 1968
S B Weiss   +3 more
openalex   +1 more source

Species Specificity of Transfer RNA. [PDF]

open access: bronze, 1963
Robert B. Loftfield   +3 more
openalex   +1 more source

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