Results 171 to 180 of about 929,368 (351)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

EF-G-catalyzed translocation of anticodon stem-loop analogs of transfer RNA in the ribosome [PDF]

, 1998
Simpson Joseph
openalex   +1 more source

Riddle of the Sphinx: Emerging Role of Transfer RNAs in Human Cancer [PDF]

, 2021
Zhilin Qiu, Qin Wang, Lei Liu, Guozheng Li, Yi Hao, Shipeng Ning, Lei Zhang, Xin Zhang, Yihai Chen, Jiale Wu, Xinheng Wang, Shuai Yang, Yao‐Xin Lin, Shouping Xu   +13 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA

, 1975
Wolfgang E. Schmidt, H.H. Arnold, H. Kersten   +2 more
openalex   +2 more sources

Engineered Transfer RNA Suppression of CFTR Nonsense Mutations [PDF]

, 2018
John D. Lueck, Adam L. Mackey, Daniel T. Infield, Marshall R. Pope, Paul B. McCray, Christopher A. Ahern   +5 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Transfer RNA acetylation regulates in vivo mammalian stress signaling. [PDF]

Sci Adv
Thalalla Gamage S, Khoogar R, Howpay Manage S, DaRos JT, Crawford MC, Georgeson J, Polevoda BV, Sanders C, Lee KA, Nance KD, Iyer V, Kustanovich A, Perez M, Thu CT, Nance SR, Amin R, Miller CN, Holewinski RJ, Das S, Meyer TJ, Koparde V, Yang A, Jailwala P, Nguyen JT, Andresson T, Hunter K, Gu S, Mock BA, Edmondson EF, Difilippantonio S, Chari R, Schwartz S, O'Connell MR, Wu CC, Meier JL.   +34 more
europepmc   +2 more sources

Transfer RNA [PDF]

, 2020
openaire   +2 more sources

Transfer RNA regulation during herpesvirus infection: Wielding a sword or raising a shield? [PDF]

PLoS Pathog
Rapchak K, Tucker JM.
europepmc   +1 more source