Results 11 to 20 of about 5,671,100 (385)

Transfer RNA-derived small RNAs in the cancer transcriptome [PDF]

open access: yesPflügers Archiv: European Journal of Physiology, 2016
The cellular lifetime includes stages such as differentiation, proliferation, division, senescence and apoptosis.These stages are driven by a strictly ordered process of transcription dynamics.
A Dueck   +38 more
core   +2 more sources

Characterization of Circulating Transfer RNA-Derived RNA Fragments in Cattle

open access: yesFrontiers in Genetics, 2015
The objective was to characterize naturally occurring circulating transfer RNA-derived RNA Fragments (tRFs) in cattle. Serum from eight clinically normal adult dairy cows was collected, and small non-coding RNAs were extracted immediately after ...
Eduardo eCasas   +2 more
doaj   +2 more sources

Transfer RNA and human disease

open access: yesFrontiers in Genetics, 2014
Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and result in very complicated clinical phenotypes. Mitochondrial tRNA (mt-tRNA) genes are hotspots for pathological mutations and over 200 mt-tRNA mutations have been linked ...
Jamie A Abbott   +2 more
doaj   +2 more sources

Tissue-specific differences in human transfer RNA expression. [PDF]

open access: yesPLoS Genetics, 2006
Over 450 transfer RNA (tRNA) genes have been annotated in the human genome. Reliable quantitation of tRNA levels in human samples using microarray methods presents a technical challenge.
Kimberly A Dittmar   +2 more
doaj   +2 more sources

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

open access: yesNature Communications, 2020
Extracellular vesicles (EV) facilitate intercellular transfer of biological material including RNA, but the regulatory mechanisms for their formation and transfer are incompletely known.
Olivier G. de Jong   +13 more
doaj   +2 more sources

RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

open access: yesNature Communications, 2019
The limited availability of high-resolution 3D RNA structures for model training limits RNA secondary structure prediction. Here, the authors overcome this challenge by pre-training a DNN on a large set of predicted RNA structures and using transfer ...
Jaswinder Singh   +3 more
doaj   +2 more sources

7-Methylguanosine Modifications in Transfer RNA (tRNA) [PDF]

open access: goldInternational Journal of Molecular Sciences, 2018
More than 90 different modified nucleosides have been identified in tRNA. Among the tRNA modifications, the 7-methylguanosine (m7G) modification is found widely in eubacteria, eukaryotes, and a few archaea.
Chie Tomikawa
openalex   +2 more sources

Complete mitochondrial genomes of two insular races of Pazala swordtails from Taiwan, China (Lepidoptera: Papilionidae: Graphium)

open access: yesMitochondrial DNA. Part B. Resources, 2021
The mitogenomes of two insular subspecies of Pazala, G. (P.) eurous asakurae and G. (P.) mullah chungianus from Taiwan Island, are reported. Both mitogenomes are circular, 15,228 bp and 15,240 bp in length respectively, and consist of 37 genes, including
Shao-Ji Hu, Xin Zhang, Kuang Duan
doaj   +1 more source

Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture

open access: yeseLife, 2023
Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the ‘transferome’) is unknown.
Sandipan Dasgupta   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy