Results 271 to 280 of about 5,671,100 (385)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors. [PDF]

Biol Psychiatry Glob Open Sci
Blaze J, Evans VD, Feria Pliego JA, Unichenko P, Javidfar B, Heissel S, Alwaseem H, Pennington Z, Cai D, Molina H, Henneberger C, Akbarian S.   +11 more
europepmc   +1 more source

Transfer RNA‐derived fragments: origins, processing, and functions

Wiley Interdisciplinary Reviews - RNA, 2011
Andrew Sobala, G. Hutvagner
semanticscholar   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Evolutionary insights from the mitochondrial genomes of invasive scale insects (Hemiptera: Coccomorpha): large-scale transfer RNA gene truncations and tandem repeat-driven intraspecific gene rearrangements. [PDF]

BMC Genomics
Ye F, Zhou JY, Li ZQ.
europepmc   +1 more source

THE TRANSFER OF MAGAZINE TRAINING BY INJECTION OF BRAIN RNA IN RATS.

, 1967
James V. McConnell, Tsuyoshi Shigehisa, Harold T. Salive   +2 more
openalex   +2 more sources

Transfer RNA as a cofactor coupling amino acid synthesis with that of protein.

Proceedings of the National Academy of Sciences of the United States of America, 1968
M. Wilcox, And, M. Nirenberg
semanticscholar   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

tRF-3a-Pro: A Transfer RNA-Derived Small RNA as a Novel Biomarker for Diagnosis of Hepatitis B Virus-Related Hepatocellular Carcinoma. [PDF]

Cell Prolif
Si J, Zou Y, Gao Y, Chen J, Jiang W, Shen X, Zhu C, Yao Q.   +7 more
europepmc   +1 more source

Alterations in lysine transfer RNA during erythroid differentiation of the Friend cell

, 1978
Lawrence Kleiman, Joanne Woodward-Jack, Robert Cedergren, Richard Dion   +3 more
openalex   +2 more sources