Results 271 to 280 of about 868,050 (310)
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Structural Studies on Transfer RNA: Crystallization of Formylmethionine and Leucine Transfer RNA's
Science, 1969Improved solvent systems were used to crystallize two different transfer RNA species. These crystals show increased mechanical and thermal stability over crystals obtained previously from a similar system. They have sufficient stability and crystalline order to be used in x-ray crystallographic studies.
H. Ishikura +7 more
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Biosynthesis of mammalian transfer RNA. Evidence for regulation by deacylated transfer RNA
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976The rate of tRNA synthesis in cultured Friend leukemia cells has been examined as a function of the variation in polyribosome structure produced by treatment with a variety of inhibitors of protein synthesis. The results indicate, in contrast to the conclusions of Bölcsföldi (Bölcsföldi, G. (1974) Exp.
Thomas A. Hamilton, Michael Litt
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The FASEB Journal, 1993
Since its theoretical inception, the tRNA molecule has been identified and many of its functions have been described in terms of its structure. However, the molecular basis for the aminoacylation specificity of tRNA has remained largely unsolved until recently, when substantial progress has disclosed fundamental aspects of this process.
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Since its theoretical inception, the tRNA molecule has been identified and many of its functions have been described in terms of its structure. However, the molecular basis for the aminoacylation specificity of tRNA has remained largely unsolved until recently, when substantial progress has disclosed fundamental aspects of this process.
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Transfer RNA nucleotidyltransferase
1990Publisher Summary All tRNA molecules contain, at the 3′ terminus, the identical-CCA sequence that is required for their acceptor and transfer functions. In prokaryotic cells, no discrete pattern has emerged. In laboratory strains of Escherichia coli , all tRNA genes sequenced encode the -CCA sequence, and mutant strains devoid of tRNA ...
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Transfer-RNA: The early adaptor
Naturwissenschaften, 1981Evolutionary history of tRNA is studied by comparative sequence analysis of two specified tRNA's at various phylogenetic levels and of tRNA families within four different species. Criteria are developed that allow 1) to distinguish between convergent and divergent evolution, 2) to determine the mechanism of divergence and 3) to estimate the degree of ...
Eigen, Manfred +1 more
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The Journal of Biochemistry, 1976
The role of cations (polyamines and Mg2+) in isoleucyl-tRNA formation catalyzed by purified isolecuyl-tRNA synthetase [EC 6.1.1.5] from Escherichia coli was studied. It was found that spermine, spermidine, and Mg2+ bind to tRNA and that when bound to these cations, tRNA acts as substrate of aminoacylation without requiring further cations.
Yoshifumi Takeda +2 more
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The role of cations (polyamines and Mg2+) in isoleucyl-tRNA formation catalyzed by purified isolecuyl-tRNA synthetase [EC 6.1.1.5] from Escherichia coli was studied. It was found that spermine, spermidine, and Mg2+ bind to tRNA and that when bound to these cations, tRNA acts as substrate of aminoacylation without requiring further cations.
Yoshifumi Takeda +2 more
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Nucleotide Sequence and Function of Transfer RNA and Precursor Transfer RNA
1973At present, we have to consider the functional interactions of the tRNA molecule without knowing its three-dimensional structure. Comparison of tRNA sequences has shown that they have a common hydrogen-bonded structure defined by the cloverleaf arrangement, and in addition they have certain common sequences or correlated sequences which may also be ...
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
Abstract 1. 1. Treatment of tRNA fMet with hydroxylamine caused specific modification of cytosine residues among a number of constituent nucleobases and only three out of the 26 cytosine residues in the tRNA were modified. The modified tRNA was found to charge methionine up to 64 % of its original acceptance. 2. 2.
Yoshiyuki Kawamura, Yoshihisa Mizuno
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Abstract 1. 1. Treatment of tRNA fMet with hydroxylamine caused specific modification of cytosine residues among a number of constituent nucleobases and only three out of the 26 cytosine residues in the tRNA were modified. The modified tRNA was found to charge methionine up to 64 % of its original acceptance. 2. 2.
Yoshiyuki Kawamura, Yoshihisa Mizuno
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On the origin of the transfer RNA molecule
Journal of Theoretical Biology, 1992Data and arguments are given in favour of the hypothesis that the primitive tRNA molecule may have originated from a direct duplication event involving one of the two halves of the tRNA molecule. It seems that a molecule capable of assuming a hairpin structure was involved as a precursor in this duplication.
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1977
When it was observed that soluble RNA (sRNA) played a vital role in protein synthesis, this low-molecular-weight species of RNA attracted much attention. The typical sRNA molecule, with a molecular weight of about 25,000 and a sedimentation constant of 4S, is a polynucleotide chain containing about 80 nucleotides.
D. S. Letham, R. E. H. Wettenhall
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When it was observed that soluble RNA (sRNA) played a vital role in protein synthesis, this low-molecular-weight species of RNA attracted much attention. The typical sRNA molecule, with a molecular weight of about 25,000 and a sedimentation constant of 4S, is a polynucleotide chain containing about 80 nucleotides.
D. S. Letham, R. E. H. Wettenhall
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