Results 21 to 30 of about 929,368 (351)
A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects
G3: Genes, Genomes, Genetics, 2022 Transfer RNAs (tRNAs) are the adaptor molecules required for reading the genetic code and producing proteins. Transfer RNA variants can lead to genome-wide mistranslation, the misincorporation of amino acids not specified by the standard genetic code ...
Joshua R Isaacson +6 more
doaj +1 more source
YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
, 2017 Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo +5 more
core +2 more sources
Mitochondrial DNA. Part B. Resources, 2019 Genetic innovation may be linked to evolutionary success, and indeed, the invasive round goby mitochondrial genome sequence carries two novel features not previously described in Benthophilinae.
Silvia Gutnik +2 more
doaj +1 more source
Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]
, 2016 Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A. +2 more
core +3 more sources
Alternative genetic code for amino acids and transfer RNA revisited
Biomolecular Concepts, 2013 The genetic code is highly conserved among all organisms and its evolution is thought to be strictly limited. However, an increasing number of studies have reported non-standard codes in prokaryotic and eukaryotic genomes.
Hamashima Kiyofumi, Kanai Akio
doaj +1 more source
Tissue-specific differences in human transfer RNA expression. [PDF]
PLoS Genetics, 2006 Over 450 transfer RNA (tRNA) genes have been annotated in the human genome. Reliable quantitation of tRNA levels in human samples using microarray methods presents a technical challenge.
Kimberly A Dittmar +2 more
doaj +1 more source
Expression profiles of serum transfer RNA-derived fragments and their potential roles in non-small cell lung cancer. [PDF]
Transl Cancer ResSong Y, Li J.
europepmc +2 more sources
Exploration of Targeted Anti-tumor Therapy, 2023 Aim: Recently, a tumor cell-platelet interaction was identified in different tumor entities, resulting in a transfer of tumor-derived RNA into platelets, named further “tumor-educated platelets (TEP)”.
Lisa T. Huber +9 more
doaj +1 more source
Transfer RNA and human disease
Frontiers in Genetics, 2014 Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and result in very complicated clinical phenotypes. Mitochondrial tRNA (mt-tRNA) genes are hotspots for pathological mutations and over 200 mt-tRNA mutations have been linked ...
Jamie A Abbott +2 more
doaj +1 more source
Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
, 2010 Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source