Results 21 to 30 of about 4,527,665 (350)
Pharmaceutics, 2021 Extracellular vesicles (EVs) are 50–1000 nm vesicles secreted by virtually any cell type in the body. They are expected to transfer information from one cell or tissue to another in a short- or long-distance way. RNA-based transfer of information via EVs
Max Piffoux +3 more
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Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]
PLoS ONE, 2017 Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse +4 more
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Annals of Translational Medicine, 2020 Transfer RNA-derived small RNA (tsRNA)s are novel non-coding RNAs, expressed in a variety of tissues and organs. Two subtypes of tsRNAs have been reported: tRNA-derived stress-induced RNA (tiRNA)s and tRNA-derived fragment (tRF)s.
Yanglei Jia, Wei Tan, Yedi Zhou
semanticscholar +1 more source
tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.
Nucleic Acids Research, 1997 We describe a program, tRNAscan-SE, which identifies 99-100% of transfer RNA genes in DNA sequence while giving less than one false positive per 15 gigabases.
T. Lowe, S. Eddy
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tRFtarget: a database for transfer RNA-derived fragment targets
Nucleic Acids Res., 2020 Transfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs and play important roles in biological and physiological processes. Prediction of tRF target genes and binding sites is crucial in understanding the biological functions of ...
Ningshan Li +3 more
semanticscholar +1 more source
tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes
Nucleic Acids Res., 2016 High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-
T. Lowe, Patricia P. Chan
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Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Ischemic stroke triggers peripheral immunosuppression, increasing the susceptibility to poststroke pneumonia that is linked with poor survival.
Katarzyna Winek +14 more
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tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes
bioRxiv, 2019 tRNAscan-SE has been widely used for transfer RNA (tRNA) gene prediction for over twenty years, developed just as the first genomes were decoded. With the massive increase in quantity and phylogenetic diversity of genomes, the accurate detection and ...
Patricia P. Chan +3 more
semanticscholar +1 more source
GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes
Nucleic Acids Res., 2015 Transfer RNAs represent the largest, most ubiquitous class of non-protein coding RNA genes found in all living organisms. The tRNAscan-SE search tool has become the de facto standard for annotating tRNA genes in genomes, and the Genomic tRNA Database ...
Patricia P. Chan, T. Lowe
semanticscholar +1 more source
A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects
G3: Genes, Genomes, Genetics, 2022 Transfer RNAs (tRNAs) are the adaptor molecules required for reading the genetic code and producing proteins. Transfer RNA variants can lead to genome-wide mistranslation, the misincorporation of amino acids not specified by the standard genetic code ...
Joshua R Isaacson +6 more
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