GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes
Nucleic Acids Res., 2015 Transfer RNAs represent the largest, most ubiquitous class of non-protein coding RNA genes found in all living organisms. The tRNAscan-SE search tool has become the de facto standard for annotating tRNA genes in genomes, and the Genomic tRNA Database ...
Patricia P. Chan, T. Lowe
semanticscholar +1 more source
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs
Nucleic Acids Research, 2018 Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular functions. Here we demonstrate that ALKBH3 is a 1-methyladenosine (m1A) and 3-methylcytidine (m3C) demethylase of tRNA.
Zhuojia Chen +9 more
semanticscholar +1 more source
Biosynthetic pathway of mitochondrial ATPase subunit 9 in Neurospora crassa [PDF]
, 1983 Subunit 9 of mitochondrial ATPase (Su9) is synthesized in reticulocyte lysates programmed with Neurospora poly A-RNA, and in a Neurospora cell free system as a precursor with a higher apparent molecular weight than the mature protein (Mr 16,400 vs.
Hennig, Bernd +3 more
core +1 more source
Modifications and functional genomics of human transfer RNA
Cell Research, 2018 Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively modified RNA with, on an average, 13 modifications per molecule.
T. Pan
semanticscholar +1 more source
The central dogma of biological homochirality: How does chiral information propagate in a prebiotic network? [PDF]
, 2023 Biological systems are homochiral, raising the question of how a racemic mixture of prebiotically synthesized biomolecules could attain a homochiral state at the network level. Based on our recent results, we aim to address a related question of how chiral information might have flowed in a prebiotic network. Utilizing the crystallization properties of
arxiv +1 more source
MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data. [PDF]
, 2017 Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly facilitated the study of tRFs.
Loher, Phillipe +2 more
core +2 more sources
Next generation sequencing reveals the complete plastome sequence of newly discovered cliff-dwelling Sonchus boulosii (Asteraceae: Cichorieae) in Morocco [PDF]
, 2019 The complete chloroplast genome sequences of newly discovered cliff-dwelling species of Sonchus, S. boulosii, were reported in this study. The S. boulosii plastome was 152,016 bp long, with the large single copy (LSC) region of 83,988 bp, the small ...
Kim, Seon-Hee +2 more
core +1 more source
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets [PDF]
, 2018 Exosomal miRNA transfer is a mechanism for cell-cell communication that is important in the immune response, in the functioning of the nervous system and in cancer.
Ball, Neil J. +11 more
core +3 more sources
Knowledge from Large-Scale Protein Contact Prediction Models Can Be Transferred to the Data-Scarce RNA Contact Prediction Task [PDF]
arXiv, 2023 RNA, whose functionality is largely determined by its structure, plays an important role in many biological activities. The prediction of pairwise structural proximity between each nucleotide of an RNA sequence can characterize the structural information of the RNA.
arxiv
, 1970 Discoba (Excavata) is an ancient group of eukaryotes with great morphological and ecological diversity. Unlike the other major divisions of Discoba (Jakobida and Euglenozoa), little is known about the mitochondrial DNAs(mtDNAs) of Heterolobosea.
Andersson, Siv G. E. +4 more
core +2 more sources