Results 41 to 50 of about 4,678,084 (301)

7-Methylguanosine Modifications in Transfer RNA (tRNA)

open access: yesInternational Journal of Molecular Sciences, 2018
More than 90 different modified nucleosides have been identified in tRNA. Among the tRNA modifications, the 7-methylguanosine (m7G) modification is found widely in eubacteria, eukaryotes, and a few archaea.
Chie Tomikawa
semanticscholar   +1 more source

ER Membrane Contact Sites: Key Platforms for Biogenesis of RNA-Containing Extracellular Vesicles

open access: yesContact, 2022
The mechanisms by which cytoplasmic cargoes such as RNAs are incorporated into extracellular vesicles (EVs) are poorly understood. In a recent article published in Developmental Cell, we describe a novel function of endoplasmic reticulum membrane contact
Bahnisikha Barman   +2 more
doaj   +1 more source

PtRFdb: a database for plant transfer RNA-derived fragments

open access: yesDatabase J. Biol. Databases Curation, 2018
Transfer RNA-derived fragments (tRFs) represent a novel class of small RNAs (sRNAs) generated through endonucleolytic cleavage of both mature and precursor transfer RNAs (tRNAs).
N. Gupta   +3 more
semanticscholar   +1 more source

Highly Sensitive Northern Hybridization Using a Rapid Protocol for Downward Alkaline Blotting of RNA

open access: yesBioTechniques, 1998
A simple and fast RNA gel blot procedureis described that uses 50 mM NaOH tosimultaneously transfer and fix RNA to apositively charged nylon membrane. TheRNA is transferred in a downward direction,and transfer is routinely completedwithin 2.5 h.
Ivan L. Ingelbrecht   +2 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Characterization of UVA-Induced Alterations to Transfer RNA Sequences

open access: yesBiomolecules, 2020
Ultraviolet radiation (UVR) adversely affects the integrity of DNA, RNA, and their nucleoside modifications. By employing liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based RNA modification mapping approaches, we identified the transfer RNA (
Congliang Sun   +2 more
doaj   +1 more source

Complete mitochondrial genome of Sinogastromyzon szechuanensis (Teleostei, Cypriniformes, Balitoridae) obtained using next-generation sequencing

open access: yesMitochondrial DNA. Part B. Resources, 2021
The complete mitogenome sequence of Sinogastromyzon szechuanensis was obtained using next generation sequencing and confirmed via overlap-PCR method.
Wei Li   +7 more
doaj   +1 more source

Platelets and tumor-associated RNA transfer.

open access: yesBlood, 2021
Until recently the nucleic acid content of platelets was considered to be fully determined by their progenitor megakaryocyte. However, it is now well understood that additional mediators (e.g.
Silvia D’Ambrosi   +2 more
semanticscholar   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

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