Results 191 to 200 of about 99,404 (289)

Aspergillus fumigatus PolX1 is an early ancestor of vertebrate terminal deoxynucleotidyl transferases. [PDF]

Nucleic Acids Res
Parveen N, Steblina S, Behera A, Benckendorff CM, Miller GJ, Davis KE, Mukherjee P.   +6 more
europepmc   +1 more source

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

BMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang, Nan Zhang, Ruiqi Yang, Qian Qiu, Jiaying Huang, Jingang Liu, Silu Li, Jonathan F. Lovell, He Ren, Yumiao Zhang   +9 more
wiley   +1 more source

Promiscuous Transferases Malonylate Furaneol Glucoside in <i>Fragaria</i> × <i>ananassa</i>. [PDF]

J Agric Food Chem
Wulanjati MP, Trinkl J, Wang X, Hoffmann T, Schwab W.   +4 more
europepmc   +1 more source

Defect‐engineered iron single‐site catalysts with tailored atomic coordination for enhanced mild photothermal therapy via triad modulation of apoptosis and ferroptosis

BMEMat, EarlyView.
A defect‐engineered triad catalyst (DMOF‐SNP‐siRNA) has been developed to enhance mild photothermal therapy for cancer treatment by addressing the limitations of heat shock protein overexpression and suboptimal therapeutic outcomes. This synergy induces potent apoptotic and ferroptotic responses, significantly enhancing the photothermal and catalytic ...
Fanghua Zhang, Wendong Liu, Zhe Hao, Haijun Lu, Jinzheng Liu, Huajie Pang, Ruizhong Zhang, Xiyan Li, Zongjie Wang, Libing Zhang   +9 more
wiley   +1 more source

Insecticide resistance in Aedes aegypti and Aedes albopictus in southern Benin: quantification, investigation of kdr mutations, and detection of detoxification enzyme activity. [PDF]

Trop Med Health
Konkon AK, Aikpon R, Hoyochi I, Zoungbédji DM, Sovi A, Salako AS, Konkon C, Dangnon B, Yahoue G, Adjovi RV, Antoine L, Ahouandjinou J, Grace NK, Adjottin B, Baba-Moussa L, Osse R, Akogbéto M, Padonou GG.   +17 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Draft genome sequence of Actinopolyspora saharensis DSM 46666, a rare actinomycete isolated from the Algerian Sahara. [PDF]

Access Microbiol
Zhou S, Saker R, Bouras N, Dif G, Mast Y, Nouioui I.   +5 more
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Comparative transcriptomic profiling of drug-metabolizing enzymes and drug transporters in rabbit ocular subtissues, liver, and duodenum. [PDF]

Drug Metab Dispos
Li M, Sanderson BJ, Hackett JL, Niyangoda SS, Gong H, Johnson MA, Wang MZ.   +6 more
europepmc   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

BMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu, Baoqin Song, Zhihao Chen, Wenzhong Li, Wanjun Liang, Xiu Wang   +5 more
wiley   +1 more source