Results 241 to 250 of about 212,981 (331)

The retaining kdo transferase that synthesizes Escherichia coli K13 capsule is deeply divergent from structurally homologous enzymes. [PDF]

J Biol Chem
Govind M, Allas MJ, Huang BS, Lowary TL, Kimber MS.   +4 more
europepmc   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Iterative Bump-and-hole engineering creates a bioorthogonal reporter for N -acetylglucosaminyltransferase I

Liu Y, Pieters S, Bineva-Todd G, Sagiroglugil M, Burnap SA, Hoddle F, Cioce A, Ohara A, Bruemmer K, Bertozzi CR, Polizzi K, Struwe WB, Rovira C, Schumann B.   +13 more
europepmc   +1 more source

Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities. [PDF]

Angew Chem Int Ed Engl
Weidler S, Bundgaard O, Hessefort M, Rädisch M, Graf CGF, Lam K, Neubauer VJ, Eisenreich J, Köhler L, Moremen KW, Steentoft C, Clausen H, Huang TY, Hung SC, Steegborn C, Weyand M, Unverzagt C.   +16 more
europepmc   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Functional Divergence of the Arg/N-Degron Pathway Between the Crop <i>Brassica rapa</i> and the Model Plant <i>Arabidopsis thaliana</i>. [PDF]

Plant Direct
Mooney BC, Garcia P, Singh SK, Graciet E.   +3 more
europepmc   +1 more source

Biocatalytic Alkylation of Ambident Nucleophiles Enables Selective N-Functionalization of Heterocycles and Late-Stage Modifications. [PDF]

Angew Chem Int Ed Engl
Ospina F, Schülke KH, Schnutenhaus M, Klein A, Desai O, Jain S, Krofta C, Stratmann L, Yang J, Gröger H, Hammer SC.   +10 more
europepmc   +1 more source

Genome sequence data of the chitinase-producing bacterium <i>Paenibacillus mucilaginosus</i> YWY-5.1. [PDF]

Data Brief
Ngoc LNT, Huynh TU, Tran DM.
europepmc   +1 more source

The Crystallography of Enzymes: A Retrospective and Beyond. [PDF]

Crystals (Basel)
Huang T, Khan J, Lakhani S, Li A, Vyas A, Hunt J, Garcia SAE, Liang B.   +7 more
europepmc   +1 more source