International Journal of Cancer, EarlyView.Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger +13 more
wiley +1 more source
Adjusting Iron Markers for Inflammation Reduces Misclassification of Iron Deficiency After Total Hip Arthroplasty. [PDF]
J Clin MedTham A +3 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background The prevalence of iron deficiency with anemia and iron deficiency without anemia (IDWA) during pregnancy have not been summarized, and evidence of the direct association of IDWA with adverse perinatal outcomes (APO) are unknown.
Lucky O. Lawani +6 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
The effect of HFE gene mutation and iron overload on sustained virological response in Egyptian chronic hepatitis C patients treated with daclatasvir and sofosbuvir. [PDF]
Korean J Intern MedKodsi EM +6 more
europepmc +1 more source
Effects of obesity, total fasting and realimentation on L-thyroxine (T4), 3,5,3', - L-triiodothyronine (T3), - 3,3',5'-L-triiodorhyronine (rT3), - thyroxine binding globulin (TBG), cortisol, thyrotophin, cortisol-binding globulin (CBG), transferrin, alpha2-haptoglobin and complement C 3 in serum [PDF]
, 1979 Bauer, M. +6 more
core
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
iNew Medicine, EarlyView.ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
Molecular detection of transferrin genetic formation as a marker for weight and growth hormones in male Arabi sheep. [PDF]
Open Vet JJawad Ali NM, Owaid JM, Nazzal AR.
europepmc +1 more source
Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities
ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley +1 more source
Interdisciplinary Medicine, EarlyView.SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu +6 more
wiley +1 more source