Results 331 to 340 of about 212,698 (347)
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The Transferrin Receptor and the Release of Iron from Transferrin
1994In a classic report detailing the role of transferrin in providing iron to human reticulocytes, Jand1 and coworkers noted that uptake of transferrin-borne iron was saturable as the concentration of transferrin in the culture medium increased, and that uptake was essentially abolished if cells were first exposed to trypsin.
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Regulation of transferrin receptor 2 protein levels by transferrin
Blood, 2004AbstractTransferrin receptor 2 (TfR2) plays a critical role in iron homeostasis because patients carrying disabling mutations in the TFR2 gene suffer from hemochromatosis. In this study, iron-responsive regulation of TfR2 at the protein level was examined in vitro and in vivo.
Marianne Wessling-Resnick, Aeisha D Robb
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Transferrin and the Transferrin Receptor: Of Magic Bullets and Other Concerns
Inflammation & Allergy-Drug Targets, 2008Transferrin (Trf) is a highly conserved serum glycoprotein mostly known for its iron transport capacity. As iron is an indispensable nutrient for cell division, Trf and its receptor have long been used as targets of pharmacological intervention mostly for cancer therapy and for diagnosis in inflammation.
de Sousa M, Macedo Mf
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ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Kenneth N. Raymond, E.A. Dertz
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Kenneth N. Raymond, E.A. Dertz
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Diagnostic value of transferrin
Clinica Chimica Acta, 2012Despite the growing interest in hepcidin and other relatively new biomarkers, guidelines and clinical pathways continue to recommend traditional markers, such as serum transferrin (Tf) and ferritin, as laboratory tests for the diagnostic evaluation of iron-related disorders.
D. Szőke, M. Panteghini
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Characterization of transferrin binding and specificity of the placental transferrin receptor
Archives of Biochemistry and Biophysics, 1983This study systematically examined the characteristics of specific binding of adult diferric transferrin to its receptor using a Triton X-100 solubilized preparation from human placentas as the receptor source. The following information was obtained. The ionic strength for maximal binding is in the range of 0.1-0.3 M NaCl.
Hajime Tsunoo, Howard H. Sussman
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The physiology of transferrin and transferrin receptors.
Physiological Reviews, 1987C A Finch, H A Huebers
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Immunohistochemical Demonstration of Transferrin and Transferrin Receptor in Mammalian Integument
Biotechnic & Histochemistry, 1997The present study demonstrates the distribution of transferrin and the transferrin receptor in the integument of eleven wild mammalian species using immunohistochemical methods. Both substances were regularly found in or near the peripheral cells of the sebaceous glands, especially of dense-haired animals.
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