Results 31 to 40 of about 137,943 (306)

Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway [PDF]

, 1992
Gene-based therapies for a variety of inherited and acquired pulmonary diseases will require the development of vectors capable of safe and efficient transfer of DNA to the respiratory epithelium.
Boucher, R. C., Rømer, Maria Unni, Boucher, Richard C., Wagner, E., Wagner, Ernst, Birnstiel, Max L., Rømer, M. U., Cotten, Matt, Cotten, M., Agarwal, Santosh, Birnstiel, M. L., Curiel, David T., Agarwal, S., Romer, M., Curiel, D. T.   +14 more
core   +1 more source

Transferrin as a source of iron for Campylobacter rectus

Journal of Oral Microbiology, 2011
Background and Objective: Campylobacter rectus is considered as one of the bacterial species of etiological importance in periodontitis. Iron-containing proteins such as transferrin are found in periodontal sites and may serve as a source of iron for ...
Daniel Grenier, Shin-ichi Tanabe
doaj   +1 more source

Polymorphism of Transferrin Gene Impacts the Mediating Effects of Psychotic Symptoms on the Relationship between Oxidative Stress and Cognition in Patients with Chronic Schizophrenia

Antioxidants, 2022
A series of studies indicated that iron distribution that partly derives from transferrin-bound iron in the peripheral nervous system in the brain may act in processes such as myelination and brain development.
Pinhong Chen, Dongmei Wang, Meihong Xiu, Dachun Chen, Blake Lackey, Hanjing E. Wu, Jin Zhou, Xiangyang Zhang   +7 more
doaj   +1 more source

Transferrin-modified cancer cell member coating hypocrellin B-derived nanomaterials for enhanced photodynamic therapy efficacy in hepatocellular carcinoma

Medicine in Drug Discovery, 2021
Hepatocellular carcinoma (HCC) has been reported to be the third common malignant tumor because of the high rate of mortality. Photosensitizers (PSs) based on the natural products have been widely used in clinical antitumor research contributed to their ...
Zhiqiang Zhang, Xianghui Li, Kai Zhao, Zhenhuan Guo, Yonglu Liu, Dai Zeng, Xueting Ban, Li Zhao, Xia Ma, Shizhong Zheng   +9 more
doaj   +1 more source

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett, Richter, Dagmar-Ulrike, Volker Briese, Jeschke, Udo, Klaus Friese, Ioannis Mylonas, Annett Streu, Udo Jeschke, Briese, Volker, Mylonas, Ioannis, Müller, Heiner, Dagmar-Ulrike Richter, Friese, Klaus, Heiner Müller   +13 more
core   +1 more source

Transferrin Receptor-Targeted Nanocarriers: Overcoming Barriers to Treat Glioblastoma

Pharmaceutics, 2022
Glioblastoma multiforme (GBM) is the most common and lethal type of brain tumor, and the clinically available approaches for its treatment are not curative.
Maria João Ramalho, Joana Angélica Loureiro, Manuel A. N. Coelho, Maria Carmo Pereira   +3 more
doaj   +1 more source

Analysis of the role or Rab4 and Rab11 in endosomal carrier formation and transferrin recycling [PDF]

, 2012
: In all eukaryotic cells, membrane transport is essential to distribute proteins from the endoplasmic reticulum to their respective destination, i.e. the Golgi, the endosomal/lysosomal system and the cell exterior. A multitude of proteins is involved in
Hirschmann, David
core   +1 more source

Dual Targeting of Cancer Cells and MMPs with Self-Assembly Hybrid Nanoparticles for Combination Therapy in Combating Cancer

Pharmaceutics, 2021
The co-delivery of chemotherapeutic agents and immune modulators to their targets remains to be a great challenge for nanocarriers. Here, we developed a hybrid thermosensitive nanoparticle (TMNP) which could co-deliver paclitaxel-loaded transferrin (PTX ...
Kai Zhang, Jingjing Li, Xiaofei Xin, Xiaoqing Du, Di Zhao, Chao Qin, Xiaopeng Han, Meirong Huo, Lei Yang, Lifang Yin   +9 more
doaj   +1 more source

Transferrin and the transferrin cycle in Belgrade rat reticulocytes

Journal of Biological Chemistry, 1993
Belgrade rats have an autosomal recessive anemia with hypochromia and microcytosis. Iron uptake into reticulocytes is approximately 20% of normal, but transferrin uptake is unimpaired. We have systematically compared the transferrin cycle in Belgrade versus normal reticulocytes to locate the defect more precisely.
M D, Garrick, K, Gniecko, Y, Liu, D S, Cohan, L M, Garrick   +4 more
openaire   +2 more sources

Delivery of Nanoparticles across the Intestinal Epithelium via the Transferrin Transport Pathway

Pharmaceutics, 2019
The aim of this study was to probe whether the transferrin (Tf) transport pathway can be exploited for intestinal delivery of nanoparticles. Tf was adsorbed on 100 nm model polystyrene nanoparticles (NP), followed by size characterisation of these ...
Jing M. Yong, Julia Mantaj, Yiyi Cheng, Driton Vllasaliu   +3 more
doaj   +1 more source