Results 161 to 170 of about 75,793 (264)

Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin

Allergy, EarlyView.
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes, Clara Lebrón‐Martín, Lucía Vallecillos‐Azor, Pablo Torres, Amene Tesfaye Ayane, Gádor Bogas, María Salas, Adriana Ariza, María Isabel Montañez, María José Torres, Carlos José Aranda, Cristobalina Mayorga   +11 more
wiley   +1 more source

The Giant Panda Transferrin Receptor Facilitates Feline Parvovirus Infection to Drive Cross-Species Transmission. [PDF]

Vet Sci
Yan Q, Hu H, Zhao S, Zhao Q, Wu R, Huang X, Wang Y, Wen Y, Zheng Y, Zhao F, Cao S, Du S, Lang Y.   +12 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Transferrin receptor 1 deficiency in smooth muscle cells attenuates vascular remodeling in hypertensive mice. [PDF]

Hypertens Res
Naito Y, Sawada H, Horimatsu T, Ohmuraya M, Asakura M, Ishihara M.   +5 more
europepmc   +1 more source

Urinary alcohol and ethyl glucuronide as a screening tool for alcohol use in pregnancy: A multicenter prospective study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this objective, anonymous study of 1053 women attending their first antenatal appointment, a surprisingly low percentage (0.38%) contained ethyl glucuronide (EtG), a metabolite of alcohol. These findings challenge previous studies that suggest that up to 60% of pregnant women in Ireland consume alcohol during pregnancy. Abstract Introduction Reports
Ciara A. McCormick, Grace Mealy, Caroline Donaghy, Patricia Gordon, Elizabeth Dunn, Pauline Carroll, Alfonso Rodriguez‐Herrera, Conrado M. Cusnaider, William Ebbitt, Peter A. McCormick, Fionnuala M. McAuliffe   +10 more
wiley   +1 more source

Translational minimal physiologically based pharmacokinetic model for transferrin receptor-mediated brain delivery of antibodies. [PDF]

MAbs
Muliaditan M, van Steeg TJ, Avery LB, Sun W, Hammond TR, Hijdra D, Choi SL, Pillai N, Leksa NC, Mavroudis PD.   +9 more
europepmc   +1 more source

Lysosome-mediated aggregation of galactose-deficient IgA1 with transferrin receptor 1 links to IgA nephropathy. [PDF]

Nat Commun
Si M, Fu J, Fang M, Lu Y, Huang J, Li H, Wang P, Liao M, Zhu J, Li P, Zhong W, Guo Z, Yang W, Ye Z, Hu H, Yu X.   +15 more
europepmc   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source